Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization.
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Old cells, new tricks: chromatin structure in senescenceMolecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Distinct chromatin signature of histone H3 variant H3.3 in human cells.Histone H3.3 and its proteolytically processed form drive a cellular senescence programmeHIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by DaxxUbinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complexThe histone chaperone DAXX maintains the structural organization of heterochromatin domainsO-linked N-acetylglucosamine transferase (OGT) interacts with the histone chaperone HIRA complex and regulates nucleosome assembly and cellular senescence.Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres.A Crowdsourced nucleus: understanding nuclear organization in terms of dynamically networked protein function.Emerging roles of ATRX in cancer.PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX.A Molecular Prospective for HIRA Complex Assembly and H3.3-Specific Histone Chaperone Function.The Histone Variant H3.3 in Transcriptional Regulation and Human Disease.Age-dependent differential expression of death-associated protein 6 (Daxx) in various peripheral tissues and different brain regions of C57BL/6 male mice.Herpesvirus Latency: On the Importance of Positioning Oneself.Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity.Epigenetic regulation in cell senescence.Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression.Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone AxisCoordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
P2860
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P2860
Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年学术文章
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2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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2013年學術文章
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name
Dynamics of histone H3.3 depos ...... heterochromatin organization.
@en
Dynamics of histone H3.3 depos ...... heterochromatin organization.
@nl
type
label
Dynamics of histone H3.3 depos ...... heterochromatin organization.
@en
Dynamics of histone H3.3 depos ...... heterochromatin organization.
@nl
prefLabel
Dynamics of histone H3.3 depos ...... heterochromatin organization.
@en
Dynamics of histone H3.3 depos ...... heterochromatin organization.
@nl
P2093
P2860
P356
P1433
P1476
Dynamics of histone H3.3 depos ...... heterochromatin organization.
@en
P2093
Daniel Fink
Manuel Stucki
Myriam Gwerder
Teresa Olbrich
P2860
P304
P356
10.4161/CC.26988
P577
2013-11-05T00:00:00Z