A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
about
Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sitesBiochemical and Structural Characterization of the Pak1-LC8 InteractionAuto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinaseThe unfolded protein response signals through high-order assembly of Ire1Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5Regulation of the Ste20-like kinase, SLK: involvement of activation segment phosphorylationIRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assemblyPAK as a therapeutic target in gastric cancerPAK signalling during the development and progression of cancerDissecting activation of the PAK1 kinase at protrusions in living cells.3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers.Identification of phosphorylation sites in betaPIX and PAK1Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sitesInteraction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish developmentAutophosphorylation within the Atg1 activation loop is required for both kinase activity and the induction of autophagy in Saccharomyces cerevisiaeP21-activated kinase in inflammatory and cardiovascular disease.PAK1 as a therapeutic target.Tyrosyl phosphorylated serine-threonine kinase PAK1 is a novel regulator of prolactin-dependent breast cancer cell motility and invasion.The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo.Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPasesUnique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signalingRegulation of cardiac excitation and contraction by p21 activated kinase-1Substrate recognition of PLCγ1 via a specific docking surface on Itk.PAK signaling in oncogenesis.A new Rac/PAK/GC/cGMP signaling pathway.Recent advances in the development of p21-activated kinase inhibitorsP21 activated kinases: structure, regulation, and functions.Targeting PAK1.Structure, biochemistry, and biology of PAK kinases.The p21-activated kinase 1 (Pak1) signalling pathway in cardiac disease: from mechanistic study to therapeutic exploration.Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activationAnalysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange.Autophosphorylation of Ser428 of EhC2PK plays a critical role in regulating erythrophagocytosis in the parasite Entamoeba histolytica.Use of a decoy peptide to purify p21 activated kinase-1 in cardiac muscle and identification of ceramide-related activation.Melanoma-associated mutants within the serine-rich domain of PAK5 direct kinase activity to mitogenic pathways.p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation
P2860
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P2860
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@ast
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@en
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@en-gb
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@nl
type
label
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@ast
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@en
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@en-gb
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@nl
prefLabel
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@ast
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@en
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@en-gb
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@nl
P2093
P50
P1476
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases
@en
P2093
André Hoelz
David E Wemmer
Jeffrey G Pelton
Patricia Pellicena
P304
P356
10.1016/J.JMB.2006.06.017
P407
P577
2006-08-11T00:00:00Z