The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response - Wikidata - wikimedia - TriplyDB

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

http://www.wikidata.org/entity/Q24297147

about

The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic Targets Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair Role of Deubiquitinating Enzymes in DNA Repair Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work The 26S proteasome is a multifaceted target for anti-cancer therapies 53BP1: pro choice in DNA repair BRCA1, a 'complex' protein involved in the maintenance of genomic stability DNA DSB repair pathway choice: an orchestrated handover mechanism Functions of the 19S complex in proteasomal degradation The 26S proteasome drives trinucleotide repeat expansions Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.Ubiquitylation, neddylation and the DNA damage response UbcH7 regulates 53BP1 stability and DSB repair Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection Molecular mechanisms of 3,3'-dichlorobenzidine-mediated toxicity in HepG2 cells.Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair Cigarette smoke alters the proteomic profile of lung fibroblasts.Biochemical mechanism of DSB end resection and its regulation.Role of p97/VCP (Cdc48) in genome stability.POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair.Genetics of proteasome diseases.2-DE Mapping of the Blue Mussel Gill Proteome: The Usual Suspects Revisited.PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination.53BP1, BRCA1, and the choice between recombination and end joining at DNA double-strand breaks.DNA damage emergency: cellular garbage disposal to the rescue?Reading, writing, and repair: the role of ubiquitin and the ubiquitin-like proteins in DNA damage signaling and repair.Deubiquitylating enzymes and DNA damage response pathways.Deubiquitylases from genes to organism.Deubiquitinases and the new therapeutic opportunities offered to cancer.Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice.USP11 Is a Negative Regulator to γH2AX Ubiquitylation by RNF8/RNF168.Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells.Dub3 controls DNA damage signalling by direct deubiquitination of H2AX.Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks.The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases.

P2860

590233e71712425b29c76124e360f88824ab2e51 b16cb6376635b9c4092da869a90221c89fa3c153

P248

Q24323354-D984138B-E75B-45C4-8289-CB3E2FAD9775 Q24617857-0CD58CD0-F6F6-43CB-BD05-2C901D95AD51 Q26741797-A70A197A-047C-4B36-B6D6-156284901E57 Q26742134-062ADF3A-9CF0-40C9-959F-F933927E24B0 Q26773800-227B251C-5093-4335-97DF-DC7A9BA81363 Q26781153-7CF091E1-FBD9-4D89-89FC-2EC9E9EAC850 Q26795764-0A895C0E-1913-4D79-9D45-959FC1484C4F Q26828847-308E1DEA-CC7F-453D-9AA6-B87D7D881F7C Q26853262-E42E0AAC-E981-4FB9-88F7-7F700A695689 Q26861805-D17DEE6F-6A40-418C-A792-B1D904CBDD70 Q26996345-F8EB1702-643B-4B02-A53A-1120F7AF4BFD Q27933260-010161D3-5D8A-4083-A95F-29D2BAC50F30 Q27935947-29F54D5E-CE04-4CCD-811C-C3CB0E4A8DAF Q28087342-6B04A4BD-182F-4E62-81EC-100EAACAFF3E Q34709157-74BEB7D9-6B4F-4DD4-BCD5-ADB0E7DA42DF Q34980915-B8C4F633-68DE-45C6-9DAE-BA5A70D24F40 Q35113557-35B2C3A5-3415-40D9-A6C3-ADF221E3A257 Q35158055-37EBA46F-EA70-4371-809F-17D22E4B0FC0 Q35358319-36496D44-937F-453E-A988-AB72085E1BC5 Q35611153-57010A48-D9AE-4CA7-976B-85CE03878B92 Q35908828-48D34318-2354-4DB5-965C-5D99D87D07AF Q36804013-1F1F37F0-2B77-4F84-9B8F-4DF9CC6A16B7 Q36839501-7F225BA4-0D2A-4268-9E13-AFE4C3A42754 Q37224708-C48966AC-A150-4F8F-AE02-57F34E2F4DF6 Q37474898-2C87B6FE-99A5-4CAC-B527-605619BE500E Q37483040-04EC826F-5F56-4476-8012-16B321BE6E1F Q37636212-D934C46A-6733-4AAD-B029-1B95FC2FBAEA Q37691802-DB3520EE-3DBF-4C9A-BBBC-E0C96B824401 Q37713592-3F7CD5F5-463A-4EEE-BE32-30650DF707A8 Q38090434-AF56860D-4597-4B8B-9E0D-37458731D9B5 Q38095917-98BCB090-5E05-4BB5-951B-AAD833694D35 Q38109871-51D85457-8FF0-4158-916D-B5DC097D4D7E Q38125278-3C57C5F7-64D7-488E-83BC-AC6256BD8F9D Q38326071-A06AFA13-0CE7-457C-BD14-87245CA36539 Q38777487-E11ED0B1-C629-425F-99C9-5C99103B9B50 Q38824349-BD9267F0-2FE3-40A0-AB4B-2C08A1CE4AA4 Q38919423-E0813C15-645C-4C53-BF69-E0260EAE56EC Q39007611-5B07406C-DD18-42AA-8C4C-48029AB6E98D Q39031491-4ABA4655-99C2-4E57-94A4-C368DB38C0D0 Q39160987-FAC84031-09D2-49D5-BC23-F34969DA9F77

P2860

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

http://www.wikidata.org/entity/Q24297147

description

2012 nî lūn-bûn

@nan

2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@ast

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@en

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@en-gb

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@nl

type

label

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@ast

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@en

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@en-gb

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@nl

prefLabel

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@ast

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@en

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@en-gb

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@nl

P1433

Q24297147-E5E9B617-F301-499A-B650-86F87DE66223

P1476

Q24297147-BA95808D-C569-43F6-A469-A37B3542EEDF

P2093

Q24297147-42D918C2-FF1E-435B-BFD6-EE221D25EAE8

Q24297147-70761870-44F9-4663-953B-5AB7619C034C

Q24297147-AB78E5A4-B7BF-49CB-AE17-411BCBD72330

Q24297147-B7A581B8-52BD-46D6-9E1D-9F4CEFE5D98E

Q24297147-C4F26F52-FDD8-4419-863A-18405BB3EA1D

Q24297147-DFAD8BC2-2BB5-4A95-8CBC-2A9C973A2ADD

P2860

Q24297147-004238DB-4060-4228-A958-9B9816C19B0F

Q24297147-0163ECEA-C619-45ED-A2B2-7EB14409726C

Q24297147-0463740A-0A9F-4472-8C47-4A411E323308

Q24297147-06CCC909-CFF0-44D7-87F0-D9C44D58D230

Q24297147-0829DEF0-1CA5-4F81-BB96-7AD59CECF547

Q24297147-099B2B44-103D-4A8C-8E6D-D158A5CC4292

Q24297147-09BC797C-D4F0-4829-B37C-BC259ADABAF8

Q24297147-0C3DE89E-E59C-4733-AE62-F657DF89FE42

Q24297147-0F25B462-826C-440B-AA62-DFA492A5F847

Q24297147-10A14012-9659-4342-885A-3D5CA3BF7489

P304

Q24297147-8A107431-6144-48F8-86F2-C33A71C1FB80

P31

Q24297147-F48EFFC0-9DFE-4BB4-8AAC-A3AA2D4629B2

P3181

Q24297147-63C116F4-3893-4142-9785-CB0AA61B4C5D

P356

Q24297147-ED451347-262F-4493-9E6B-8D6F31532BEE

P407

Q24297147-084AC991-17B5-4D68-9755-6B2C57FBA272

P433

Q24297147-C3D1D5D3-A60D-4618-8739-42EF163F4121

P478

Q24297147-4A6C417D-2C8A-4632-A235-86BEB8936FFE

P50

Q24297147-9CA2F94F-7317-47D2-88E3-13DD86B1BBB8

Q24297147-B0E9E0FB-CA05-4C0E-AE15-FAB60FE05BFE

Q24297147-B305730C-9A65-451F-AA42-2EDAC53FFF15

Q24297147-FCA1EB6A-D279-4058-A299-6CD44CCA802D

P577

Q24297147-BCA898EC-5E37-485D-B55F-0B357249AAC3

P5875

Q24297147-68A4365D-09BD-4976-B606-DFA5A014CE04

P698

Q24297147-189A0E92-56DA-4CCA-A9E4-177680CF97E2

P921

Q24297147-4DE947C9-9C58-4C9D-B314-20E5AF77A283

Q24297147-7FFC0BFC-312E-42E0-9E72-176390CA5AC8

Q24297147-C53F307A-2E36-498A-AC53-8B4FE1DAA13B

P932

Q24297147-B86CCB38-5E48-4C90-85CD-D6ED8F8B7993

P3181

P356

P1433

The EMBO Journal

P1476

The proteasomal de-ubiquitinat ...... uble-strand DNA break response

@en

P2093

Alexander J Garvin

http://www.w3.org/2001/XMLSchema#string

Helen R Stone

http://www.w3.org/2001/XMLSchema#string

James Beesley

http://www.w3.org/2001/XMLSchema#string

Junying Jia

http://www.w3.org/2001/XMLSchema#string

Laura R Butler

http://www.w3.org/2001/XMLSchema#string

Vandna Shah

http://www.w3.org/2001/XMLSchema#string

P2860

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Regulation of cell cycle progression and gene expression by H2A deubiquitination

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair

P304

3918-3934

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4250956

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/EMBOJ.2012.232

http://www.w3.org/2001/XMLSchema#string

P407

P433

19

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P50

Joanna R Morris

P577

2012-08-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

230713411

http://www.w3.org/2001/XMLSchema#string

P698

22909820

http://www.w3.org/2001/XMLSchema#string

P921

protein K63-linked deubiquitination

Proteasome 26S subunit, non-ATPase 14

protein ubiquitination

P932

3463844

http://www.w3.org/2001/XMLSchema#string