The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
about
The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break responseA ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair networkRing finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damageReal Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand BreaksStructural basis for role of ring finger protein RNF168 RING domainDNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease ActivitiesThe DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisSUMO-mediated regulation of DNA damage repair and responsesThe RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choiceRegulation of Ku-DNA association by Yku70 C-terminal tail and SUMO modificationNon-homologous end joining: emerging themes and unanswered questions.BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.Pathway choice in DNA double strand break repair: observations of a balancing act.Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis.Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.Non-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process.Spatiotemporal dynamics of DNA repair proteins following laser microbeam induced DNA damage - when is a DSB not a DSB?Inhibition of UBE2D3 expression attenuates radiosensitivity of MCF-7 human breast cancer cells by increasing hTERT expression and activity.Regulation of the DNA damage response by ubiquitin conjugation.SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells.Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joiningmiR-214-mediated downregulation of RNF8 induces chromosomal instability in ovarian cancer cellsThe Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesisRNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids.Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damageCHFR is important for the first wave of ubiquitination at DNA damage sitesPhosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phaseAn SCF complex containing Fbxl12 mediates DNA damage-induced Ku80 ubiquitylation.RIF1 counteracts BRCA1-mediated end resection during DNA repairRole of p97/VCP (Cdc48) in genome stability.Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1.Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis.Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy.RNF8 promotes epithelial-mesenchymal transition of breast cancer cells.DNA double strand break repair via non-homologous end-joining.Regulation of the DNA damage response on male meiotic sex chromosomesHerpes Simplex Virus-Type1 (HSV-1) Impairs DNA Repair in Cortical Neurons.TopBP1 controls BLM protein level to maintain genome stability
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P248
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P2860
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
description
2012 nî lūn-bûn
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2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@ast
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@en
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@en-gb
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@nl
type
label
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@ast
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@en
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@en-gb
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@nl
prefLabel
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@ast
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@en
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@en-gb
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@nl
P2860
P921
P3181
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P1476
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
@en
P2093
P2860
P2888
P3181
P356
10.1038/NSMB.2211
P407
P577
2012-02-01T00:00:00Z
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1045057423