The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
about
Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppressionCalcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cellsPolo-like kinase 1, on the rise from cell cycle regulation to prostate cancer developmentSelective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brainRegulatory functional territory of PLK-1 and their substrates beyond mitosis.Where no RNA polymerase has gone before: novel functional transcripts derived from the ribosomal intergenic spacer.SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosisHormonal induction of polo-like kinases (Plks) and impact of Plk2 on cell cycle progression in the rat ovary.A novel anti-tumor inhibitor identified by virtual screen with PLK1 structure and zebrafish assay.Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo.From Plk1 to Plk5: functional evolution of polo-like kinasesThe Polo-like kinase PLKA in Aspergillus nidulans is not essential but plays important roles during vegetative growth and development.Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer TreatmentGenetic mutations associated with metastatic clear cell renal cell carcinoma.Cytoskeletal architecture and cell motility remain unperturbed in mouse embryonic fibroblasts from Plk3 knockout mice.Plk2 regulates mitotic spindle orientation and mammary gland developmentPolo-like kinase 1 inhibitors in mono- and combination therapies: a new strategy for treating malignancies.Targeting of polo-like kinases and their cross talk with Aurora kinases--possible therapeutic strategies in human acute myeloid leukemia?Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes.Current assessment of polo-like kinases as anti-tumor drug targets.Polo-like kinases: structural variations lead to multiple functions.Antitumoral effect of PLK-1-inhibitor BI2536 in combination with cisplatin and docetaxel in squamous cell carcinoma cell lines of the head and neck.Understanding the Polo Kinase machine.The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression.p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress.Augmented expression of Polo-like kinase 1 is a strong predictor of shorter cancer-specific overall survival in early stage breast cancer at 15-year follow-up.Mitotic Kinases and p53 Signaling.Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.Polo-like kinase 3, hypoxic responses, and tumorigenesis.Schistosoma mansoni Polo-like kinases and their function in control of mitosis and parasite reproduction.Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling.
P2860
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P2860
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
description
2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2010 թվականի մայիսին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@ast
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@en
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@en-gb
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@nl
type
label
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@ast
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@en
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@en-gb
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@nl
prefLabel
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@ast
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@en
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@en-gb
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@nl
P2093
P2860
P3181
P356
P1476
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
@en
P2093
David L Myer
El Mustapha Bahassi
Peter J Stambrook
William Z Bernstein
Zdenek Andrysik
P2860
P304
P3181
P356
10.1093/NAR/GKQ011
P407
P577
2010-05-01T00:00:00Z