The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.
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Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activationNovel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cellsThe tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complexThe RASSF1A tumor suppressor restrains anaphase-promoting complex/cyclosome activity during the G1/S phase transition to promote cell cycle progression in human epithelial cellsLocal activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizesThe tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complexThe scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell deathHYAL1 and HYAL2 inhibit tumour growth in vivo but not in vitroRegulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by RasRBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignanciesGenetic and Chromosomal Aberrations and Their Clinical Significance in Renal NeoplasmsThe significance of genetics for cholangiocarcinoma developmentRASSF tumor suppressor gene family: biological functions and regulationA new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinomaRASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumorsTumor suppressor and hepatocellular carcinomaMenin determines K-RAS proliferative outputs in endocrine cellsDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMMicrotubule segment stabilization by RASSF1A is required for proper microtubule dynamics and Golgi integrity.Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastomaFrequent promoter hypermethylation of the APC and RASSF1A tumour suppressors in parathyroid tumours.The Ras-association domain family (RASSF) members and their role in human tumourigenesis.Epigenetic alterations in RASSF1A in human aberrant crypt fociIndividual retinal progenitor cells display extensive heterogeneity of gene expression.High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer.Simultaneous down-regulation of tumor suppressor genes RBSP3/CTDSPL, NPRL2/G21 and RASSF1A in primary non-small cell lung cancer.Qualitative and quantitative promoter hypermethylation patterns of the P16, TSHR, RASSF1A and RARβ2 genes in papillary thyroid carcinoma.Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinomaHuman mammary cancer progression model recapitulates methylation events associated with breast premalignancy.Genomic distance entrained clustering and regression modelling highlights interacting genomic regions contributing to proliferation in breast cancerRole of Epigenetics in Uveal MelanomaRASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers.Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosisRASSF6 promotes p21(Cip1/Waf1)-dependent cell cycle arrest and apoptosis through activation of the JNK/SAPK pathway in clear cell renal cell carcinoma.Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoterPromoter hypermethylation inactivates CDKN2A, CDKN2B and RASSF1A genes in sporadic parathyroid adenomasPredictive utility of circulating methylated DNA in serum of melanoma patients receiving biochemotherapy.Tumor suppressor RASSF1A promoter: p53 binding and methylation.Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors.DNA methylation of cancer genome.
P2860
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P2860
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The RASSF1A tumor suppressor b ...... nhibits cyclin D1 accumulation
@nl
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@ast
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@en
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@en-gb
type
label
The RASSF1A tumor suppressor b ...... nhibits cyclin D1 accumulation
@nl
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@ast
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@en
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@en-gb
prefLabel
The RASSF1A tumor suppressor b ...... nhibits cyclin D1 accumulation
@nl
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@ast
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@en
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@en-gb
P2093
P2860
P921
P1476
The RASSF1A tumor suppressor b ...... hibits cyclin D1 accumulation.
@en
P2093
John Minna
Latha Shivakumar
Michael A White
Richard Pestell
Toshiyuki Sakamaki
P2860
P304
P356
10.1128/MCB.22.12.4309-4318.2002
P407
P577
2002-06-01T00:00:00Z