NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling
about
USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMOcIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoformsLUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMOHuman ALKBH7 is required for alkylation and oxidation-induced programmed necrosisMany stimuli pull the necrotic trigger, an overviewRipped to deathPoly-ubiquitination in TNFR1-mediated necroptosisAn outline of necrosome triggersFueling the flames: Mammalian programmed necrosis in inflammatory diseasesNecroptosis: an emerging type of cell death in liver diseasesPhotoreceptor cell death and rescue in retinal detachment and degenerationsViral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathwaysRIPK-dependent necrosis and its regulation by caspases: a mystery in five actsRegulatory non-coding RNA: new instruments in the orchestration of cell deathDNA Damage: From Chronic Inflammation to Age-Related DeteriorationDie another way--non-apoptotic mechanisms of cell deathNuclear DNA damage signalling to mitochondria in ageingCARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cellsRIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activationThe intersection between DNA damage response and cell death pathwaysDepletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosisCrosstalk in NF-κB signaling pathwaysNrf2 amplifies oxidative stress via induction of Klf9.RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3NecroptosisEtanercept blocks inflammatory responses orchestrated by TNF-α to promote transplanted cell engraftment and proliferation in rat liver.The role of 8-oxoguanine DNA glycosylase-1 in inflammationRIP1 maintains DNA integrity and cell proliferation by regulating PGC-1α-mediated mitochondrial oxidative phosphorylation and glycolysisThe API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling.Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodelingLuteolin inhibits human keratinocyte activation and decreases NF-κB induction that is increased in psoriatic skin.E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin.Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics.ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion.Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1.TGFβ receptor 1: an immune susceptibility gene in HPV-associated cancer.IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB ActivationInhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growthDNA damage induces NF-κB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion.Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-α-induced shock.
P2860
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P2860
NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@ast
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@en
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@en-gb
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@nl
type
label
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@ast
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@en
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@en-gb
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@nl
prefLabel
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@ast
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@en
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@en-gb
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@nl
P3181
P1433
P1476
NEMO and RIP1 control cell fat ...... ia TNF-α feedforward signaling
@en
P2093
Avi Ashkenazi
Sharon Biton
P304
P3181
P356
10.1016/J.CELL.2011.02.023
P407
P577
2011-04-01T00:00:00Z