Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis - Wikidata - wikimedia - TriplyDB

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

http://www.wikidata.org/entity/Q29036177

about

Post-translational modifications as key regulators of TNF-induced necroptosis Molecular crosstalk between apoptosis, necroptosis, and survival signaling An outline of necrosome triggers Programmed necrosis in the cross talk of cell death and inflammation Mitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular disease Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells Molecular and cellular mechanisms responsible for cellular stress and low-grade inflammation induced by a super-low dose of endotoxin Insights into battles between Mycobacterium tuberculosis and macrophages.Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death.TAK1 control of cell death.Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma.Regulated cell death in AKI.Revisiting caspases in sepsis.RIP kinases: key decision makers in cell death and innate immunity.RIPK3 expression in cervical cancer cells is required for PolyIC-induced necroptosis, IL-1α release, and efficient paracrine dendritic cell activation Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.Activation of innate antiviral immune response via double-stranded RNA-dependent RLR receptor-mediated necroptosis.Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome.Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.Necroptosis: an alternative cell death program defending against cancer.Evolutionary divergence of the necroptosis effector MLKL.IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils.Mitochondrial-Shaping Proteins in Cardiac Health and Disease - the Long and the Short of It!Cell death controlling complexes and their potential therapeutic role.Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1.Necroptosis: A new way of dying?Necroptosis: a potential, promising target and switch in acute pancreatitis.Induction of Apoptosis in TNF-Treated L929 Cells in the Presence of Necrostatin-1.Gut mucosal DAMPs in IBD: from mechanisms to therapeutic implications.A real-time fluorometric method for the simultaneous detection of cell death type and rate.CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway.Post-translational control of RIPK3 and MLKL mediated necroptotic cell death.Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine

P2860

Q26744244-55E2ECD7-493A-4544-B810-EE70938C244B Q26745680-88EEF617-9047-40C6-B7EF-3BE0FDF41B5F Q26751108-46722E5C-0D85-4D39-B888-71A7B5AD93A0 Q27026709-6BCC1EAF-F7F3-4180-B8E3-5BA3C31C2D2C Q28084134-DB1FC2C1-1594-44FC-BA73-A570CCF4AD12 Q30408769-30F84413-882C-4E9D-8570-8D1BDC31036E Q30844792-EA6928AF-7CD2-4627-9667-DF1B6DEB028A Q33718511-14C37163-5D9F-45F4-8AD8-6B496BF8940D Q34268873-1D118C41-9ECC-466F-8B0B-F81FD55BB73F Q34409204-5B764E5D-954C-4B51-81EC-D50A8E464314 Q34413437-4B2C363B-9EF2-4578-AFC6-46A4ED0B6FC1 Q34541689-FD289B9A-E449-43DF-800E-B8AFECD5BE87 Q34568839-439F584A-CC8F-44A8-B22C-0112D4CE1BFB Q34662282-8E2A8801-FF3D-4EBA-BC40-2BA16E87184A Q34924104-07B95A92-F95C-4E8B-9DB1-2790AC6A6E70 Q35832188-478BBBCA-E982-4F7F-8106-D3F3E9D566F8 Q36077924-0CA46C41-C0BE-4818-920F-D6E3E18FC11E Q36162984-E0855919-A888-46A2-B9AA-279245A4180A Q36347085-388DFF81-FF10-432B-96D1-3B7BE0D4A618 Q36386948-6E37D7A3-D53E-4FCB-BAB1-B862D4D234C0 Q36645227-5BB12F33-395D-403E-8F1F-04998DDB669C Q36674720-26F3DF41-8124-498D-9591-3D5BB8804CB7 Q36751262-B42F1B57-A600-42B4-AF4D-7BB6671E2435 Q36880241-415003DD-87C3-4852-B25F-8A8A7E68FE0D Q37098819-F74CAC27-8571-4AD1-85A8-64C977A45C90 Q37376164-EFE599EA-F59B-492A-9E6F-C0194C2401E5 Q37412541-27909509-E580-4409-BDA9-541163CB7BC8 Q37465889-0F0BD88E-2F54-4F79-8122-3B74D40BF975 Q37694547-08D9B837-1436-4B64-8880-FA46E32E54CC Q38260863-D73EC108-FE9E-4324-92B6-DC0A757998E5 Q38530635-3BC2F214-4D09-40EB-B43A-602A7CEB1118 Q38559586-A10B9AC5-65A0-4AC3-8FC3-8519CF9755C4 Q38619561-7FC59373-F6D3-4F63-974F-B9B4536E4584 Q38741243-CD0B06E3-D815-4FFD-AC20-70F66D276DEB Q38756562-991CECCC-9CDD-4E5E-86FC-CB49B378C148 Q38758184-24334362-9DB8-45F4-90F5-79A3D0F5F150 Q38792072-5162065E-EE6B-4AB5-B2A6-99BF77CD07A3 Q38825538-1F2608EB-5FCE-4C3E-8BB6-FD0A9A4AE861 Q38829463-DF980B5A-E5A6-48B4-B799-2142B2709032 Q38881033-FD43DE3A-916C-4F8F-B746-B8E5D02574C0

P2860

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

http://www.wikidata.org/entity/Q29036177

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Depletion of RIPK3 or MLKL blo ...... PK1 kinase-dependent apoptosis

@ast

Depletion of RIPK3 or MLKL blo ...... PK1 kinase-dependent apoptosis

@en

type

label

Depletion of RIPK3 or MLKL blo ...... PK1 kinase-dependent apoptosis

@ast

Depletion of RIPK3 or MLKL blo ...... PK1 kinase-dependent apoptosis

@en

prefLabel

Depletion of RIPK3 or MLKL blo ...... PK1 kinase-dependent apoptosis

@ast

Depletion of RIPK3 or MLKL blo ...... PK1 kinase-dependent apoptosis

@en

P1433

Q29036177-E542DBCA-1816-4572-B46A-F16F7691076B

P1476

Q29036177-18BA8E49-C7CF-4920-8128-A167662ECB8E

P2093

Q29036177-0F131921-68FC-416D-B520-A77EB3906039

Q29036177-1FC514F2-2606-4445-9905-908F5DB189A2

Q29036177-23A66346-E68C-4EE6-ADBD-91912159CDD8

Q29036177-43E18598-F9C3-415A-8FE2-EF64763E144D

Q29036177-4F22C010-20CB-4D14-82E4-F3B37733CCB9

Q29036177-607591D8-887A-4C1F-9441-524B0CCF62D5

Q29036177-9E009A2A-3F66-41E3-9112-13024B7CEC04

Q29036177-FBCA1090-FEBA-4F25-A704-66156AF1CE95

Q29036177-FE8F46FC-9497-48E2-823F-25180224F6AB

P2860

Q29036177-02FAAB75-BA99-4BC8-AD90-F24FD9FEF5B9

Q29036177-0657BA07-E3B6-4C92-BFAD-624E44E0E26E

Q29036177-1624A81B-F9B4-4559-B2F1-3135CF95890B

Q29036177-2425F609-1718-4A94-AB42-9D9AE8D6C23B

Q29036177-2A8E1FC9-50B0-4D1C-96F5-3C9437B270A0

Q29036177-2BBF3F45-725D-4523-A6CB-A9E9544DC419

Q29036177-2FCA8C24-8138-4D0D-A632-3B21693D46FA

Q29036177-3655527C-D19E-4552-8FCE-1A792A3CBC82

Q29036177-41338315-D835-49C2-9F06-36737CC85551

Q29036177-4DECD0E6-5641-41F5-81AA-2F21CE4EE2F5

P304

Q29036177-61AC26AE-52BD-469B-9226-4A663A99F7FF

P31

Q29036177-3F6D5128-96F1-4E60-9465-9136806F10DB

P3181

Q29036177-370C65BC-A73F-4E89-A2F6-3F1E0F178D2B

P356

Q29036177-8843168E-F3A0-4CA4-B7B4-DEAB68E01568

P433

Q29036177-8EC726E7-758D-43CC-B2EC-86D0BA594D72

P478

Q29036177-203A7096-1232-4DFB-9CE2-DE70E534C978

P50

Q29036177-079B83DC-61F1-4376-8D0E-EF8019D6E558

Q29036177-3FCAA7DE-AC86-4D44-99A6-753FF4984897

Q29036177-7913AE26-BD19-429D-B0AA-9D76039BC53F

Q29036177-D803CEFA-FA89-4440-B759-8F8FC18833C3

Q29036177-FAB723C5-ED83-4076-B758-A3749C205FA8

P577

Q29036177-A22D920B-1269-4833-A329-D9E7905A23BF

P5875

Q29036177-795BDE3D-E716-4639-843C-485F4443DF72

P698

Q29036177-6F93B910-EF69-48A0-A842-7436FEC29E97

P921

Q29036177-BEDD87D7-C116-42EE-950D-416DB2AE625F

P932

Q29036177-23739096-EB3A-4F94-9727-FF85390CAA7F

P3181

P356

P1433

Cell Death and Disease

P1476

Depletion of RIPK3 or MLKL blo ...... PK1 kinase-dependent apoptosis

@en

P2093

A Goncalves

http://www.w3.org/2001/XMLSchema#string

C Van den Haute

http://www.w3.org/2001/XMLSchema#string

I Bruggeman

http://www.w3.org/2001/XMLSchema#string

N Takahashi

http://www.w3.org/2001/XMLSchema#string

Q Remijsen

http://www.w3.org/2001/XMLSchema#string

R Roelandt

http://www.w3.org/2001/XMLSchema#string

T V Berghe

http://www.w3.org/2001/XMLSchema#string

V Baekelandt

http://www.w3.org/2001/XMLSchema#string

V Goossens

http://www.w3.org/2001/XMLSchema#string

P2860

NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

TNF-alpha induces two distinct caspase-8 activation pathways

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

Mechanisms of mitophagy

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

P304

e1004

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2455795

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/CDDIS.2013.531

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Peter Vandenabeele

Sasker Grootjans

Mathieu Jm Bertrand

Nele Vanlangenakker

Yves Dondelinger

P577

2014-01-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

259769587

http://www.w3.org/2001/XMLSchema#string

P698

24434512

http://www.w3.org/2001/XMLSchema#string

P921

P932

4040672

http://www.w3.org/2001/XMLSchema#string