Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway
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Bortezomib sensitizes non-small cell lung cancer to mesenchymal stromal cell-delivered inducible caspase-9-mediated cytotoxicity.NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5.How to target apoptosis signaling pathways for the treatment of pediatric cancersIdentification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.Carbenoxolone enhances TRAIL-induced apoptosis through the upregulation of death receptor 5 and inhibition of gap junction intercellular communication in human glioma.Survivin inhibitor YM-155 sensitizes tumor necrosis factor- related apoptosis-inducing ligand-resistant glioma cells to apoptosis through Mcl-1 downregulation and by engaging the mitochondrial death pathwayBortezomib enhances antigen-specific cytotoxic T cell responses against immune-resistant cancer cells generated by STAT3-ablated dendritic cells.γ-Secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets.Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications.Targeting malignant mitochondria with therapeutic peptides.Preclinical models for pediatric solid tumor drug discovery: current trends, challenges and the scopes for improvement.Bortezomib sensitizes human glioblastoma cells to induction of apoptosis by type I interferons through NOXA expression and Mcl-1 cleavageDual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death.Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells.Laminarin-induced apoptosis in human colon cancer LoVo cells.Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism.Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation.ABT-737 promotes tBid mitochondrial accumulation to enhance TRAIL-induced apoptosis in glioblastoma cells.RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex.Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link.Polo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis.NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis.TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.Role of cysteine 288 in nucleophosmin cytoplasmic mutations: sensitization to toxicity induced by arsenic trioxide and bortezomib.The proteins (12 and 15 kDa) isolated from heat-killed Lactobacillus plantarum L67 induces apoptosis in HT-29 cells.Repeated exposure of epithelial cells to apoptotic cells induces the specific selection of an adaptive phenotype: Implications for tumorigenesis
P2860
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P2860
Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@ast
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@en
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@en-gb
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@nl
type
label
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@ast
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@en
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@en-gb
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@nl
prefLabel
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@ast
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@en
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@en-gb
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@nl
P50
P921
P1476
Bortezomib primes neuroblastom ...... r to the mitochondrial pathway
@en
P2093
Dietrich von Schweinitz
Ivonne Naumann
P304
P356
10.1158/1078-0432.CCR-10-2451
P407
P577
2011-05-15T00:00:00Z