Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.
about
Targeting protein kinases to reverse multidrug resistance in sarcoma.Volasertib suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.Cell cycle proteins as promising targets in cancer therapyThe GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.Impact of Mediterranean diet on metabolic syndrome, cancer and longevity.JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis.Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor.Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines.Polo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis.Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death.Identification of volasertib-resistant mechanism and evaluation of combination effects with volasertib and other agents on acute myeloid leukemia.Anti-apoptotic effects of autophagy via ROS regulation in microtubule-targeted and PDGF-stimulated vascular smooth muscle cells.
P2860
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P2860
Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Identification of synthetic le ...... crotubule-destabilizing drugs.
@en
type
label
Identification of synthetic le ...... crotubule-destabilizing drugs.
@en
prefLabel
Identification of synthetic le ...... crotubule-destabilizing drugs.
@en
P2860
P356
P1476
Identification of synthetic le ...... crotubule-destabilizing drugs.
@en
P2860
P2888
P304
P356
10.1038/CDD.2015.59
P50
P577
2015-05-29T00:00:00Z