Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome trafficking

Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome trafficking

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http://www.wikidata.org/entity/Q24298929
Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseasesCharacterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formationA Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesisLoss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal traffickingMice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome traffickingComponents of the antigen processing and presentation pathway revealed by gene expression microarray analysis following B cell antigen receptor (BCR) stimulationComplex genetics of amyotrophic lateral sclerosis.Sequencing of random Euplotes crassus macronuclear genes supports a high frequency of +1 translational frameshifting.Molecular and cellular pathways of neurodegeneration in motor neurone diseaseAnti-ALS activity of alsin, the product of the ALS2 gene, and activity-dependent neurotrophic factor.Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis.Age-dependent deterioration of locomotion in Drosophila melanogaster deficient in the homologue of amyotrophic lateral sclerosis 2.The N-terminal membrane occupation and recognition nexus domain of Arabidopsis phosphatidylinositol phosphate kinase 1 regulates enzyme activity.Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.RAB5 GEFs exchange GTP for GDP on RAB5The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis
P2860

Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome trafficking

Item
http://www.wikidata.org/entity/Q24298929
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@ast
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@en
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@en-gb
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@nl
type
label
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@ast
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@en
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@en-gb
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@nl
prefLabel
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@ast
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@en
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@en-gb
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Homo-oligomerization of ALS2 t ...... nction on endosome trafficking
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921