Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT
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The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendritesElectrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studiesCharacterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosisStructural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramidePromotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated proteinFFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregationHuman VAP-C negatively regulates hepatitis C virus propagationIntracellular trafficking of ceramide by ceramide transfer proteinCasein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelinRegulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer proteinInter-organelle ER-endolysosomal contact sites in metabolism and disease across evolutionAutophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALSPhosphoinositides: tiny lipids with giant impact on cell regulationA VAMP-associated protein, PVA31 is involved in leaf senescence in Arabidopsis.CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface.Ceramide transfer protein deficiency compromises organelle function and leads to senescence in primary cellsAmyotrophic lateral sclerosis-linked mutant VAPB inclusions do not interfere with protein degradation pathways or intracellular transport in a cultured cell modelChlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular developmentStructural Basis for the Golgi Association by the Pleckstrin Homology Domain of the Ceramide Trafficking Protein (CERT)Crystal structure of the pleckstrin homology domain from the ceramide transfer protein: implications for conformational change upon ligand bindingTrans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae.Structural, stability, dynamic and binding properties of the ALS-causing T46I mutant of the hVAPB MSP domain as revealed by NMR and MD simulationsMitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant miceCoordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport.Interaction between the motor protein prestin and the transporter protein VAPAThe amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality controlProtein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes.Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells.Bridging the gap: membrane contact sites in signaling, metabolism, and organelle dynamics.Acute perturbations in Golgi organization impact de novo sphingomyelin synthesisA Trypanosoma brucei protein required for maintenance of the flagellum attachment zone and flagellar pocket ER domains.Oligomerization of ZFYVE27 (Protrudin) is necessary to promote neurite extension.Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2.Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesisInsights into the mechanisms of sterol transport between organelles.VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity.Ultrastructural relationship of the phagophore with surrounding organelles.Association between DNA methylation and multidrug resistance in human glioma SHG-44 cellsModulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2.
P2860
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P2860
Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@ast
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@en
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@en-gb
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@nl
type
label
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@ast
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@en
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@en-gb
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@nl
prefLabel
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@ast
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@en
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@en-gb
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@nl
P2093
P921
P356
P1476
Efficient trafficking of ceram ...... interacting FFAT motif of CERT
@en
P2093
Keigo Kumagai
Kentaro Hanada
Masahiro Nishijima
Miyuki Kawano
P304
P356
10.1074/JBC.M605032200
P407
P577
2006-10-06T00:00:00Z