The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control
about
Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALSDrosophila as a model for unfolded protein response researchAmyotrophic lateral sclerosis-linked mutant VAPB inclusions do not interfere with protein degradation pathways or intracellular transport in a cultured cell modelLigand-dependent localization and function of ORP-VAP complexes at membrane contact sites.Shared mechanisms between Drosophila peripheral nervous system development and human neurodegenerative diseasesA genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis.Induction of excessive endoplasmic reticulum stress in the Drosophila male accessory gland results in infertility.A fruitful endeavor: modeling ALS in the fruit flyALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells.Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response.VAMP-associated Proteins (VAP) as Receptors That Couple Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Proteostasis with Lipid Homeostasis.Insights into ALS pathomechanisms: from flies to humans.Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.Iron and Neurodegeneration: Is Ferritinophagy the Link?Mitochondria-Associated Membranes (MAMs): Overview and Its Role in Parkinson's Disease.The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic SignificanceNeuronal overexpression of human VAPB slows motor impairment and neuromuscular denervation in a mouse model of ALS.Mitigating Motor Neuronal Loss in C. elegans Model of ALS8.Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular FunctionMCTP is an ER-resident calcium sensor that stabilizes synaptic transmission and homeostatic plasticityBiomarkers of Amyotrophic Lateral Sclerosis: Current Status and Interest of Oxysterols and Phytosterols.Mutations in glycyl-tRNA-synthetase impair mitochondrial metabolism in neurons.
P2860
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P2860
The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The amyotrophic lateral sclero ...... for ER protein quality control
@ast
The amyotrophic lateral sclero ...... for ER protein quality control
@en
type
label
The amyotrophic lateral sclero ...... for ER protein quality control
@ast
The amyotrophic lateral sclero ...... for ER protein quality control
@en
prefLabel
The amyotrophic lateral sclero ...... for ER protein quality control
@ast
The amyotrophic lateral sclero ...... for ER protein quality control
@en
P2093
P2860
P50
P356
P1476
The amyotrophic lateral sclero ...... for ER protein quality control
@en
P2093
Hiroshi Tsuda
Sreeparna Pradhan
Yong Q Lin
P2860
P304
P356
10.1093/HMG/DDT594
P577
2013-11-23T00:00:00Z