Overexpression of human alanine:glyoxylate aminotransferase in Escherichia coli: renaturation from guanidine-HCl and affinity for pyridoxal phosphate co-factor
about
Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type IHydrogen/deuterium exchange- and protease digestion-based screening assay for protein-ligand binding detection.Four of the most common mutations in primary hyperoxaluria type 1 unmask the cryptic mitochondrial targeting sequence of alanine:glyoxylate aminotransferase encoded by the polymorphic minor allele.Protein homeostasis defects of alanine-glyoxylate aminotransferase: new therapeutic strategies in primary hyperoxaluria type I.Primary hyperoxaluria type III--a model for studying perturbations in glyoxylate metabolism.Role of low native state kinetic stability and interaction of partially unfolded states with molecular chaperones in the mitochondrial protein mistargeting associated with primary hyperoxaluria.Effects of alanine:glyoxylate aminotransferase variants and pyridoxine sensitivity on oxalate metabolism in a cell-based cytotoxicity assay.Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with primary hyperoxaluria type I.Effective enhancement of Pseudomonas stutzeri D-phenylglycine aminotransferase functional expression in Pichia pastoris by co-expressing Escherichia coli GroEL-GroES.In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase.Folding Defects Leading to Primary Hyperoxaluria.glyoxylate + alanine => glycine + pyruvateS250F variant associated with aromatic amino acid decarboxylase deficiency: molecular defects and intracellular rescue by pyridoxine.
P2860
Q24298393-29281BD6-CDF1-47BC-AB78-5071BAE147F3Q33546018-F1027752-D294-4D4D-BEE6-6EE442CC2BB7Q36562007-9A6DEB07-D731-4B83-90A1-F015DFADE577Q38129886-501E31C0-D263-4B31-97FF-3BB228944F34Q39325975-C40CBC4C-BF3D-4687-B015-3C2DC1BAB3A2Q39628392-254996A1-F6B5-45F9-802C-0A7305973129Q40015456-FB1FBCC6-D11F-4215-8915-9613A868E16EQ40821949-4E8843E1-6061-4E69-B1F5-60A54E68E6E6Q41702063-E0F6CF27-44D4-4C46-97B1-F09346A9FB31Q42037146-90A2A16E-44B1-4052-A9BF-2285CE94F64DQ47602222-9118CC8C-7676-46B5-B9B1-E070C3BDD6B5Q50295146-FFBFE3F1-6FAD-48E4-915F-B47FDC1C72AEQ51755232-B6C93CBD-6262-4330-BBA0-C37781368451
P2860
Overexpression of human alanine:glyoxylate aminotransferase in Escherichia coli: renaturation from guanidine-HCl and affinity for pyridoxal phosphate co-factor
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@ast
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@en
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@en-gb
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@nl
type
label
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@ast
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@en
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@en-gb
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@nl
prefLabel
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@ast
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@en
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@en-gb
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@nl
P921
P1476
Overexpression of human alanin ...... pyridoxal phosphate co-factor
@en
P2093
Steve G Wong
P356
10.1016/J.PEP.2004.11.004
P407
P577
2005-05-01T00:00:00Z