The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint
about
Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1p31comet blocks Mad2 activation through structural mimicryShugoshin is a Mad1/Cdc20-like interactor of Mad2Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpointThe APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.The multifaceted roles of the HORMA domain in cellular signalingA role of WT1 in cell division and genomic stabilityCep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 DimerAn Alternative Conformation of the T-Cell Receptor α Constant RegionStructural Basis of Recruitment of DNA Polymerase by Interaction between REV1 and REV7 ProteinsStructural insights into the assembly of human translesion polymerase complexesA HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagyStructure of the mitotic checkpoint complexStructure of human Mad1 C-terminal domain reveals its involvement in kinetochore targetingMultiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidaseStructure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiationAutomated macromolecular model building for X-ray crystallography using ARP/wARP version 7Lessons from making the Structural Classification of Proteins (SCOP) and their implications for protein structure modellingA Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly CheckpointGenetic instability in budding and fission yeast-sources and mechanismsInterdomain Contacts Control Native State Switching of RfaH on a Dual-Funneled LandscapeProtein dynamism and evolvability.Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex.Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex.Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.Molecular basis of APC/C regulation by the spindle assembly checkpoint.Conserved CDC20 cell cycle functions are carried out by two of the five isoforms in Arabidopsis thalianaOne step closer to understanding mammalian macroautophagy initiation: Interplay of 2 HORMA architectures in the ULK1 complex.The influence of catalysis on mad2 activation dynamics.Molecular dynamics simulation on the conformational transition of the mad2 protein from the open to the closed state.Regulation of APC/C activators in mitosis and meiosis.Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: a mechanism for aneuploidy in cancer.Proteins that switch foldsUsing default constraints of the spindle assembly checkpoint to estimate the associated chemical rates.WT1 interacts with MAD2 and regulates mitotic checkpoint functionUbiquitin D is correlated with colon cancer progression and predicts recurrence for stage II-III disease after curative surgery.The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregationPhosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition.Protein dynamics governed by interfaces of high polarity and low packing density.
P2860
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P2860
The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@ast
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@en
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@en-gb
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@nl
type
label
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@ast
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@en
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@en-gb
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@nl
prefLabel
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@ast
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@en
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@en-gb
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@nl
P3181
P1433
P1476
The Mad2 conformational dimer: ...... he spindle assembly checkpoint
@en
P2093
Lucia Massimiliano
Marina Mapelli
P304
P3181
P356
10.1016/J.CELL.2007.08.049
P407
P577
2007-11-16T00:00:00Z