p31comet blocks Mad2 activation through structural mimicry
about
Integrative annotation of variants from 1092 humans: application to cancer genomicsCrystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1Shugoshin is a Mad1/Cdc20-like interactor of Mad2Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpointAPC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachmentMTBP plays a crucial role in mitotic progression and chromosome segregationThe multifaceted roles of the HORMA domain in cellular signalingA role of WT1 in cell division and genomic stabilityTRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint responseInsights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 DimerStructural Basis of Recruitment of DNA Polymerase by Interaction between REV1 and REV7 ProteinsStructure of the mitotic checkpoint complexThe APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly CheckpointSpatiotemporal regulation of the anaphase-promoting complex in mitosisIn-silico modeling of the mitotic spindle assembly checkpointConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex.Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint.The influence of catalysis on mad2 activation dynamics.Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer.Molecular dynamics simulation on the conformational transition of the mad2 protein from the open to the closed state.Regulation of APC/C activators in mitosis and meiosis.Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cellsNek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: a mechanism for aneuploidy in cancer.Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet).Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing proteinWT1 interacts with MAD2 and regulates mitotic checkpoint functionThe dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregationPhosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition.p31comet Promotes disassembly of the mitotic checkpoint complex in an ATP-dependent processThe chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteinsThe Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex.Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31(comet)p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachmentMutual regulation between the spindle checkpoint and APC/C.p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
P2860
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P2860
p31comet blocks Mad2 activation through structural mimicry
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
p31comet blocks Mad2 activation through structural mimicry
@ast
p31comet blocks Mad2 activation through structural mimicry
@en
p31comet blocks Mad2 activation through structural mimicry
@en-gb
p31comet blocks Mad2 activation through structural mimicry
@nl
type
label
p31comet blocks Mad2 activation through structural mimicry
@ast
p31comet blocks Mad2 activation through structural mimicry
@en
p31comet blocks Mad2 activation through structural mimicry
@en-gb
p31comet blocks Mad2 activation through structural mimicry
@nl
altLabel
p31comet Blocks Mad2 Activation through Structural Mimicry
@en
prefLabel
p31comet blocks Mad2 activation through structural mimicry
@ast
p31comet blocks Mad2 activation through structural mimicry
@en
p31comet blocks Mad2 activation through structural mimicry
@en-gb
p31comet blocks Mad2 activation through structural mimicry
@nl
P2093
P2860
P50
P3181
P1433
P1476
p31comet blocks Mad2 activation through structural mimicry
@en
P2093
P2860
P304
P3181
P356
10.1016/J.CELL.2007.08.048
P407
P577
2007-11-16T00:00:00Z