Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3
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COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phaseStructural insights of the MLF1/14-3-3 interactionIsolation and characterization of cytoplasmic cyclin D1 mutantsShuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformationMyeloma overexpressed 2 (Myeov2) regulates L11 subnuclear localization through Nedd8 modificationMyeloid leukemia factor 1 associates with a novel heterogeneous nuclear ribonucleoprotein U-like moleculeExome analysis reveals differentially mutated gene signatures of stage, grade and subtype in breast cancers.Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stabilityA phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma.Sperm and spermatids contain different proteins and bind distinct egg factors.Estrogen induced breast cancer is the result in the disruption of the asymmetric cell division of the stem cell.The COP1 E3-ligase interacts with FIP200, a key regulator of mammalian autophagy.The COP9 signalosome and vascular function: intriguing possibilities?Myeloid leukemia factor is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis.Knockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathwayCSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner.Distinctive genotypes in infants with T-cell acute lymphoblastic leukaemia.RETRACTED: The COP9 signalosome interacts with and regulates interferon regulatory factor 5 protein stability.Role of nucleophosmin in acute myeloid leukemia.Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer.Roles of COP9 signalosome in cancer.Spotlight on the role of COP1 in tumorigenesis.Nuclear receptor-binding protein 1: a novel tumour suppressor and pseudokinase.Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN.Control of RUNX-induced repression of Notch signaling by MLF and its partner DnaJ-1 during Drosophila hematopoiesis.Genetic factors conferring metastasis in osteosarcoma.Constitutive photomorphogenesis protein 1 (COP1) and COP9 signalosome, evolutionarily conserved photomorphogenic proteins as possible targets of melatonin.Endoplasmic reticulum stress sensitizes cells to DNA damage-induced apoptosis through p53-dependent suppression of p21(CDKN1A).Roles of Multifunctional COP9 Signalosome Complex in Cell Fate and Implications for Drug Discovery.Drosophila myeloid leukemia factor acts with DREF to activate the JNK signaling pathway.Depletion of CSN5 inhibits Ras-mediated tumorigenesis by inducing premature senescence in p53-null cells.CSN1 inhibits c-Jun phosphorylation and down-regulates ectopic expression of JNK1Small mitochondrial ARF (smARF) is located in both the nucleus and cytoplasm, induces cell death, and activates p53 in mouse fibroblasts.Myeloid leukemia factor: a return ticket from human leukemia to fly hematopoiesis.Cellular senescence bypass screen identifies new putative tumor suppressor genes.Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines.Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3.Stable form of JAB1 enhances proliferation and maintenance of hematopoietic progenitors.Widespread transcriptional changes pre-empt the critical pelagic-benthic transition in the vetigastropod Haliotis asinina.The myeloid leukemia factor interacts with COP9 signalosome subunit 3 in Drosophila melanogaster.
P2860
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P2860
Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@ast
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@en
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@en-gb
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@nl
type
label
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@ast
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@en
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@en-gb
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@nl
prefLabel
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@ast
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@en
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@en-gb
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@nl
P2093
P2860
P921
P356
P1433
P1476
Myeloid leukemia factor 1 regu ...... via COP9 signalosome subunit 3
@en
P2093
Jun-ya Kato
Kiichiro Tomoda
Mari Umehara
Noriko Yoneda-Kato
Yukinobu Arata
P2860
P304
P356
10.1038/SJ.EMBOJ.7600656
P407
P577
2005-05-04T00:00:00Z