Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
about
NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingTSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translationSpecific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitinationMyeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3Antiviral action of the tumor suppressor ARFTranscription-independent ARF regulation in oncogenic stress-mediated p53 responsesMass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cellsAKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosisNucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosomeA novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stabilityNucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cellsp14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activityNucleophosmin is essential for ribosomal protein L5 nuclear exportRibosomal protein S9 is a novel B23/NPM-binding protein required for normal cell proliferationA novel ARF-binding protein (LZAP) alters ARF regulation of HDM2APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic miceTargeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.N-terminal polyubiquitination and degradation of the Arf tumor suppressorCre-lox-regulated conditional RNA interference from transgenesA non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and functionShuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformationImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionRapid asymmetric evolution of a dual-coding tumor suppressor INK4a/ARF locus contradicts its functionMolecules that target nucleophosmin for cancer treatment: an updateStructural Consequences of Nucleophosmin Mutations in Acute Myeloid LeukemiaStructural polymorphism in the N-terminal oligomerization domain of NPM1Tumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell LeukemiamiR-10 in development and cancerDivorcing ARF and p53: an unsettled caseARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathwayPolyamine depletion induces nucleophosmin modulating stability and transcriptional activity of p53 in intestinal epithelial cellsRole of nucleophosmin in embryonic development and tumorigenesisNucleophosmin is required for DNA integrity and p19Arf protein stabilityThe 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stressA ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growthGLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer.Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stressesGLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARFA proteomics approach for the identification of nucleophosmin and heterogeneous nuclear ribonucleoprotein C1/C2 as chromatin-binding proteins in response to DNA double-strand breaks.
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Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Physical and functional intera ...... protein with nucleophosmin/B23
@ast
Physical and functional intera ...... protein with nucleophosmin/B23
@en
Physical and functional intera ...... protein with nucleophosmin/B23
@nl
type
label
Physical and functional intera ...... protein with nucleophosmin/B23
@ast
Physical and functional intera ...... protein with nucleophosmin/B23
@en
Physical and functional intera ...... protein with nucleophosmin/B23
@nl
prefLabel
Physical and functional intera ...... protein with nucleophosmin/B23
@ast
Physical and functional intera ...... protein with nucleophosmin/B23
@en
Physical and functional intera ...... protein with nucleophosmin/B23
@nl
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P3181
P1476
Physical and functional intera ...... protein with nucleophosmin/B23
@en
P2093
Charles J Sherr
David Bertwistle
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P304
P3181
P356
10.1128/MCB.24.3.985-996.2004
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P577
2004-02-01T00:00:00Z