WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork
about
Human RECQL5 participates in the removal of endogenous DNA damageStimulation of flap endonuclease-1 by the Bloom's syndrome proteinPhysical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicasesInteraction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndromeRoles of Werner syndrome protein in protection of genome integrityModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesHuman premature aging, DNA repair and RecQ helicasesThe interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNARoles of ChlR1 DNA helicase in replication recovery from DNA damageCharacterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediatesFANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1.RecQ helicases: guardian angels of the DNA replication fork.Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicaseMechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand.Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNAHuman RECQL5beta stimulates flap endonuclease 1Delineation of WRN helicase function with EXO1 in the replicational stress responseXRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damageSubstrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases.More forks on the road to replication stress recoveryNovel function of the flap endonuclease 1 complex in processing stalled DNA replication forksMechanism of nucleic acid unwinding by SARS-CoV helicase.Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1.The pur protein family: genetic and structural features in development and disease.The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.Impact of age-associated cyclopurine lesions on DNA repair helicases.Functional regulation of FEN1 nuclease and its link to cancerRoles of the Werner syndrome RecQ helicase in DNA replication.Accelerated in vivo epidermal telomere loss in Werner syndrome.The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks.RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast geneticsDNA helicases involved in DNA repair and their roles in cancerDNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion.Human RecQ helicases in DNA repair, recombination, and replication.Intrinsic ssDNA annealing activity in the C-terminal region of WRN.Regulation of chromatin structure by poly(ADP-ribosyl)ation.
P2860
Q24298591-AB5BF386-B3B1-499F-87C2-96FC1041145CQ24302463-692AD030-FE90-49AE-8CD6-DD5D487DE68FQ24305559-B743CCC8-CCD0-438A-8015-D1505BEA8AA8Q24337192-6926295C-4320-4E38-9713-039AC886B028Q24643050-757C0761-4248-4090-9155-EB9EF29E7B7AQ24644033-7A5FBB9B-FD23-428C-A881-C462B1CCF55FQ24680996-E8C39182-679B-41D4-B868-88930FF00DDDQ24814897-ABE58336-42FF-494F-91A3-D351903B8ED6Q28119141-9E5EC9FB-8611-4840-BF8D-7429BD99F214Q28540907-BF526785-B28D-457E-A71C-2F78BE5B37AAQ30863349-B6DDB149-81EF-44A8-B66C-26AA16CB5074Q33230386-1FF791D8-4D0E-4020-AC71-93CC8134B92DQ33292399-06F8E7FD-97FD-47D2-AE89-1A10061EA6F4Q33314341-ADC255E5-8213-41EB-8B50-94283B8988BBQ33347075-E29C152E-6BCE-47AB-8D90-DB518FAA87B0Q33415023-F6E29C57-F887-4062-86EF-897778A9B869Q33529100-F3A980B9-8D27-484E-8EC4-C66794F066FEQ33871215-3F66E314-1005-43E9-9DF8-187B527DA191Q33945750-38901E0A-A9E6-497B-B819-32B73BC5995CQ33970153-0B93045B-68AC-41C3-9A39-0CBEA1E47E60Q34077785-7369E94A-3FB6-43D2-B4E4-86CE06E9FC4BQ34161464-ADF07DD6-5AE1-4E7F-9F59-B4667F0808DCQ34166526-190C6A53-DBD2-42DE-97F9-ED8B8C859360Q34277309-0433243F-ED69-4015-82F6-2294469B3CA7Q34419570-F632DBB4-ACD3-404E-AC52-FF296DD933C5Q34423435-202B1AB3-EBC4-4285-8FCE-B25DF10FDC1EQ34499459-89EAD47E-A90B-4324-B95F-D343E70C9F77Q34534194-CD029D3E-CF08-47ED-9390-B6C34D48F917Q34542484-FA434EF1-B2FD-4AEF-A3A7-08661528111EQ34559690-68246794-0E86-4276-AF72-F2E0401F0371Q34812299-C9E8D78E-68CC-4214-850C-DF701B2E9BA0Q35052092-16A1D3DD-8D35-448E-BC30-33524F059169Q35156843-A920A076-A30F-4362-A034-910869E0DA3EQ35638929-7D25B636-896C-4BE9-BACB-D2CF3DA1A585Q35869772-5BE3A788-8013-4564-8095-A442B5641A16Q35961508-88B78D1A-B8C6-4A23-8376-4DA27D3FF7E9Q36003726-89793F93-9BF1-4CF2-A331-34CD83D53974Q36101160-1F7A800C-9851-4330-BCF9-E29B2B8F0F68Q36101209-E6B5CAA9-4DD0-4EEB-A55E-88096681E0CEQ36204365-891FB648-C4CF-489A-A398-FE52B8F12E94
P2860
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
WRN helicase and FEN-1 form a ...... ated with the replication fork
@ast
WRN helicase and FEN-1 form a ...... ated with the replication fork
@en
WRN helicase and FEN-1 form a ...... ated with the replication fork
@en-gb
WRN helicase and FEN-1 form a ...... ated with the replication fork
@nl
type
label
WRN helicase and FEN-1 form a ...... ated with the replication fork
@ast
WRN helicase and FEN-1 form a ...... ated with the replication fork
@en
WRN helicase and FEN-1 form a ...... ated with the replication fork
@en-gb
WRN helicase and FEN-1 form a ...... ated with the replication fork
@nl
prefLabel
WRN helicase and FEN-1 form a ...... ated with the replication fork
@ast
WRN helicase and FEN-1 form a ...... ated with the replication fork
@en
WRN helicase and FEN-1 form a ...... ated with the replication fork
@en-gb
WRN helicase and FEN-1 form a ...... ated with the replication fork
@nl
P2093
P2860
P3181
P356
P1476
WRN helicase and FEN-1 form a ...... ated with the replication fork
@en
P2093
Grigory L Dianov
Henry C Driscoll
Joshua A Sommers
Robert A Bambara
Robert M Brosh
Sudha Sharma
P2860
P304
P3181
P356
10.1091/MBC.E03-08-0567
P407
P577
2004-02-01T00:00:00Z