Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide
about
Newly discovered angiogenesis inhibitors and their mechanisms of actionTanshinone I inhibits tumor angiogenesis by reducing Stat3 phosphorylation at Tyr705 and hypoxia-induced HIF-1α accumulation in both endothelial and tumor cellsTriptolide inhibits ovarian cancer cell invasion by repression of matrix metalloproteinase 7 and 19 and upregulation of E-cadherinLow-dose triptolide in combination with idarubicin induces apoptosis in AML leukemic stem-like KG1a cell line by modulation of the intrinsic and extrinsic factors.Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.Terpenoids: natural products for cancer therapy.HIF-1 in cancer therapy: two decade long story of a transcription factor.LB-1 Exerts Antitumor Activity in Pancreatic Cancer by Inhibiting HIF-1α and Stat3 Signaling.Triptolide, a Chinese herbal extract, enhances drug sensitivity of resistant myeloid leukemia cell lines through downregulation of HIF-1α and Nrf2.Triptolide augments the effects of 5-lipoxygenase RNA interference in suppressing pancreatic tumor growth in a xenograft mouse model.Efficacy and safety of Tripterygium wilfordii Hook F for CKD in Mainland China: A systematic review and meta-analysis.C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells.
P2860
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P2860
Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Increased accumulation of hypo ...... antitumor effect of triptolide
@ast
Increased accumulation of hypo ...... antitumor effect of triptolide
@en
Increased accumulation of hypo ...... antitumor effect of triptolide
@en-gb
Increased accumulation of hypo ...... antitumor effect of triptolide
@nl
type
label
Increased accumulation of hypo ...... antitumor effect of triptolide
@ast
Increased accumulation of hypo ...... antitumor effect of triptolide
@en
Increased accumulation of hypo ...... antitumor effect of triptolide
@en-gb
Increased accumulation of hypo ...... antitumor effect of triptolide
@nl
prefLabel
Increased accumulation of hypo ...... antitumor effect of triptolide
@ast
Increased accumulation of hypo ...... antitumor effect of triptolide
@en
Increased accumulation of hypo ...... antitumor effect of triptolide
@en-gb
Increased accumulation of hypo ...... antitumor effect of triptolide
@nl
P2093
P2860
P356
P1433
P1476
Increased accumulation of hypo ...... antitumor effect of triptolide
@en
P2093
Jian-Ming Feng
Lin-Jiang Tong
Yuan-Chao Li
Ze-Hong Miao
Zhao-Li Zhou
P2860
P2888
P356
10.1186/1476-4598-9-268
P407
P577
2010-01-01T00:00:00Z
P5875
P6179
1048597040