Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation
about
On the origin of Tibetans and their genetic basis in adapting high-altitude environmentsIncreased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolideRegulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive elementIdentification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alphaExploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish modelsMYC, Metabolism, and CancerThe hypoxia-inducible factor pathway, prolyl hydroxylase domain protein inhibitors, and their roles in bone repair and regenerationIsolation and characterization of renal erythropoietin-producing cells from genetically produced anemia miceComputational and experimental characterization of dVHL establish a Drosophila model of VHL syndromePHD2: from hypoxia regulation to disease progressionPlacental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2Hypoxia-inducible factor prolyl-hydroxylase 2 senses high-salt intake to increase hypoxia inducible factor 1alpha levels in the renal medullaHIF hydroxylation and cellular oxygen sensing.Multiscale models of angiogenesisProlyl hydroxylase PHD3 activates oxygen-dependent protein aggregation.Genetic adaptation to extreme hypoxia: study of high-altitude pulmonary edema in a three-generation Han Chinese familyIncreased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system.Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha.Identification of transcriptome induced in roots of maize seedlings at the late stage of waterlogging.Abnormalities in oxygen sensing define early and late onset preeclampsia as distinct pathologies.Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lungInhibition of hypoxia-inducible factor-targeting prolyl hydroxylase domain-containing protein 2 (PHD2) enhances matrix synthesis by human chondrocytes.Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells.Immunohistochemical analysis of the mechanistic target of rapamycin and hypoxia signalling pathways in basal cell carcinoma and trichoepithelioma.iTRAQ: a method to elucidate cellular responses to mycotoxin zearalenone.Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1α protein synthesis.The amiloride derivative phenamil attenuates pulmonary vascular remodeling by activating NFAT and the bone morphogenetic protein signaling pathway.Translational control of collagen prolyl 4-hydroxylase-alpha(I) gene expression under hypoxia.Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.Molecular characterization and mRNA expression of two key enzymes of hypoxia-sensing pathways in eastern oysters Crassostrea virginica (Gmelin): hypoxia-inducible factor α (HIF-α) and HIF-prolyl hydroxylase (PHD).Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cellsExpression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer.Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer.The Caenorhabditis elegans rhy-1 gene inhibits HIF-1 hypoxia-inducible factor activity in a negative feedback loop that does not include vhl-1.Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus.Combination therapy targeting cancer metabolism.Involvement of hypoxia-inducible transcription factors in polycystic kidney disease.
P2860
Q21560852-D5071018-C9F1-4274-91CF-C8EF11465B19Q24302071-B7C66448-68DF-4B99-B603-B167CE831D89Q24528175-CD1C3197-A781-4E5A-B71E-740305C62194Q24651502-BC12303A-CB2E-457F-863E-C4D59A6CAA26Q26778116-7724BFEA-F9E8-45A2-B275-6F85DF897C72Q26783555-4488BF64-A636-4710-8D52-98D6492F41E5Q26861237-643D7AB0-EBED-4903-B54F-6E7E87C445F3Q27317145-B815388C-1482-4760-8021-2BB0FDE8365CQ27336383-B93C30B6-5CC8-4383-8AF7-3D9415F3CA04Q28069316-830F08BD-6939-4019-84AC-33D535D91F0BQ28508549-9B5468AB-FDE7-4E89-8032-7E521EA3166AQ28567251-784E78E0-50B2-4B06-B570-AA173A8FEBEFQ30164092-33F32166-C11B-49AE-8181-5129068C9A4EQ30432668-CDADDA43-3358-4F74-AE48-D2776A217D06Q30481841-033AB19B-FFE9-4492-A690-8FC0AE6089C5Q30528610-06AA6CD7-2781-4FE8-8C3F-F90D89D57894Q33247514-0AEC63CB-884D-460D-92BD-7D0E67A132B2Q33614677-85A04C42-268E-4CA8-9592-AAF456424257Q33644391-8C7C8D13-9777-46EB-BF0E-B3FB9203AE90Q33662015-4245D94A-301F-489B-9082-8D4D8F0DB436Q33672322-3A1653BD-E67B-40EB-85DA-5CC4D20D4608Q33725645-23CFE805-F550-462F-B260-0D036DC686DDQ33757944-5CAB9CBF-67AE-44F3-98F6-5CCD97F21708Q33900675-8EC8279B-197F-449A-AAA8-D37CA9EA4534Q33966774-710C3650-D23B-4612-ACFD-60F66C5EA758Q34075508-DF819A6E-DC9A-456C-9D28-0EEDF14D7C15Q34122334-C894962C-C366-4798-9EE8-5D74AF88491EQ34315989-BCC1EAAD-0611-4213-BD68-A8798B36C733Q34482963-21BC58B3-DBE2-42BF-A30D-5339556FF7E2Q34528387-4AEC937C-92ED-4EFE-94FB-E55EB4CAB2B0Q34546985-2E6446F7-8A7E-45B7-8706-CE199AC4358EQ34691368-B898C873-2776-4DC4-90D8-A3BA886A203FQ35007537-E88C722E-B7C6-4BA5-81B4-E5E34BA39DF4Q35022857-D6C4E863-03B9-44E7-93EE-EDD65CCBADB7Q35032951-B8878089-28AC-43CE-8568-046B5EB5FE93Q35136674-4C24FEB6-D6B1-4347-9588-F92AE2121A95Q35175988-1E9322BC-E850-42E1-8904-D7EE47FC6BE3Q35588285-292CEBDD-C3C5-48D8-9390-CB7807FE0BEBQ35606350-6A6397AD-D348-460D-8BE4-D49EEDF2EDB0Q35781329-1A25D45F-CB35-4DFC-9843-358F0A0DC1D3
P2860
Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation
description
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/10/03)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/10/03)
@nl
наукова стаття, опублікована в жовтні 2003
@uk
name
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@ast
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@en
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@nl
type
label
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@ast
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@en
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@nl
prefLabel
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@ast
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@en
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@nl
P2093
P3181
P356
P1476
Hypoxia up-regulates prolyl hy ...... responses during reoxygenation
@en
P2093
Christian Frelin
Eric Duplan
Gisela D'Angelo
Nicole Boyer
Paul Vigne
P304
38183–38187
P3181
P356
10.1074/JBC.M302244200
P407
P577
2003-10-03T00:00:00Z