Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion
about
Mutations in the SLC2A9 gene cause hyperuricosuria and hyperuricemia in the dogMolecular physiology of urate transportThe multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminusUrate Handling in the Human BodyUricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patientsMutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemiaClinical and functional characterization of URAT1 variantsHomozygous SLC2A9 mutations cause severe renal hypouricemia.Effects of irbesartan on serum uric acid levels in patients with hypertension and diabetesMetabolic syndrome, alcohol consumption and genetic factors are associated with serum uric acid concentrationA case of renal hypouricemia and a G774A gene mutation causing acute renal injury that was improved by hemodialysis.Study of Nitrosative Stress in 'Pregnancy Induced Hypertension'.The genetics of gout: towards personalised medicine?Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population.Paracellular route is the major urate transport pathway across the blood-placental barrierReassessing serum urate targets in the management of refractory gout: can you go too low?Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo.Clinical review. Kidney stones 2012: pathogenesis, diagnosis, and management.Complex analysis of urate transporters SLC2A9, SLC22A12 and functional characterization of non-synonymous allelic variants of GLUT9 in the Czech population: no evidence of effect on hyperuricemia and gout.Multiple organic anion transporters contribute to net renal excretion of uric acidUric acid level has a U-shaped association with loss of kidney function in healthy people: a prospective cohort study.Recurrent exercise-induced acute renal failure in a young Pakistani man with severe renal hypouricemia and SLC2A9 compound heterozygosity.Recurrent exercise-induced acute kidney injury by idiopathic renal hypouricemia with a novel mutation in the SLC2A9 gene and literature reviewNo association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW.Gout, genetics and ABC transporters.Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeuticsTotal saponins from Discorea nipponica makino ameliorate urate excretion in hyperuricemic rats.Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant ReceptorsDiscovery of URAT1 SNPs and association between serum uric acid levels and URAT1.The heart of drug discovery and development: rational target selection.Clinical characteristics of acute renal failure with severe loin pain and patchy renal vasoconstriction.Analysis of mutations in the urate transporter 1 (URAT1) gene of Japanese patients with hypouricemia in northern Japan and review of the literature.The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression.Hyperfiltration and uricosuria in adolescents with type 1 diabetes.Management of gout.Novel allelic variants and evidence for a prevalent mutation in URAT1 causing renal hypouricemia: biochemical, genetics and functional analysis.SLC2A9--a fructose transporter identified as a novel uric acid transporter.Prevalence and possible causes of hypouricemia at a tertiary care hospital.Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.Novel drug discovery strategies for gout.
P2860
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P2860
Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
name
Clinical and molecular analysi ...... ene on urinary urate excretion
@ast
Clinical and molecular analysi ...... ene on urinary urate excretion
@en
Clinical and molecular analysi ...... ene on urinary urate excretion
@en-gb
Clinical and molecular analysi ...... ene on urinary urate excretion
@nl
type
label
Clinical and molecular analysi ...... ene on urinary urate excretion
@ast
Clinical and molecular analysi ...... ene on urinary urate excretion
@en
Clinical and molecular analysi ...... ene on urinary urate excretion
@en-gb
Clinical and molecular analysi ...... ene on urinary urate excretion
@nl
prefLabel
Clinical and molecular analysi ...... ene on urinary urate excretion
@ast
Clinical and molecular analysi ...... ene on urinary urate excretion
@en
Clinical and molecular analysi ...... ene on urinary urate excretion
@en-gb
Clinical and molecular analysi ...... ene on urinary urate excretion
@nl
P2093
P3181
P1476
Clinical and molecular analysi ...... ene on urinary urate excretion
@en
P2093
Hitoshi Endou
Ichiro Hisatome
Kimiyoshi Ichida
Makoto Hosoyamada
Miho Hikita
Tatsuo Hosoya
P304
P3181
P356
10.1097/01.ASN.0000105320.04395.D0
P407
P577
2004-01-01T00:00:00Z