Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics
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Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association studyIdentification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria boxBlood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystalsUric acid: the past decadeUric acid as one of the important factors in multifactorial disorders--facts and controversies.Febuxostat: the evidence for its use in the treatment of hyperuricemia and goutPolymorphisms in the presumptive promoter region of the SLC2A9 gene are associated with gout in a Chinese male population.High plasma uric acid concentration: causes and consequences.Orthopaedic case of the month: medial knee pain in a 69-year-old man.Multiple organic anion transporters contribute to net renal excretion of uric acidOverview of Serum Uric Acid Treatment Targets in Gout: Why Less Than 6 mg/dL?Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4.New and improved strategies for the treatment of goutTNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.Population pharmacokinetics and exposure-uric acid analyses after single and multiple doses of ABT-639, a calcium channel blocker, in healthy volunteers.Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers.High-normal serum uric acid is associated with impaired glomerular filtration rate in nonproteinuric patients with type 1 diabetes.Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levelsSLC2A9--a fructose transporter identified as a novel uric acid transporter.Gout. Novel therapies for treatment of gout and hyperuricemia.Novel drug discovery strategies for gout.Hyperuricemia and gout: new concepts in diagnosis and management.Drug discovery for hyperuricemia.Recent advances in understanding and managing goutDiet-independent relevance of serum uric acid for blood pressure in a representative population sample.Computational Lexical Analysis of the Language Commonly Used to Describe Gout.The development of an effective synthetic route of lesinurad (RDEA594).Self-sufficient control of urate homeostasis in mice by a synthetic circuit.Urate-Lowering Therapy Ameliorates Kidney Function in Type 2 Diabetes Patients With Hyperuricemia.Chronic kidney disease and the risk of incident gout among middle-aged men: a seven-year prospective observational study.Uricosuric agents decrease the plasma urate level in rats by concomitant treatment with topiroxostat, a novel xanthine oxidoreductase inhibitor.Enhancement of pharmacological effects of uricosuric agents by concomitant treatment with pyrazinamide in rats.[Crystal-induced arthritis--old but important].
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P2860
Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Recent developments in our und ...... antihyperuricemic therapeutics
@ast
Recent developments in our und ...... antihyperuricemic therapeutics
@en
type
label
Recent developments in our und ...... antihyperuricemic therapeutics
@ast
Recent developments in our und ...... antihyperuricemic therapeutics
@en
prefLabel
Recent developments in our und ...... antihyperuricemic therapeutics
@ast
Recent developments in our und ...... antihyperuricemic therapeutics
@en
P2093
P2860
P356
P1476
Recent developments in our und ...... antihyperuricemic therapeutics
@en
P2093
David A Bushinsky
Michael A Becker
Robert Terkeltaub
P2860
P2888
P356
10.1186/AR1909
P478
P577
2006-04-12T00:00:00Z
P5875
P6179
1039896024