Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).
about
Identification and characterization of mitochondrial targeting sequence of human apurinic/apyrimidinic endonuclease 1APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase betaEarly steps in the DNA base excision/single-strand interruption repair pathway in mammalian cellsActivation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATPDynamic Regulation of APE1/Ref-1 as a Therapeutic Target ProteinThe current state of eukaryotic DNA base damage and repairRepair of oxidative DNA damage and cancer: recent progress in DNA base excision repairEmerging roles of the nucleolus in regulating the DNA damage response: the noncanonical DNA repair enzyme APE1/Ref-1 as a paradigmatical exampleReactive oxygen species (ROS) homeostasis and redox regulation in cellular signalingProteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interactionThe Anti-Apoptotic Properties of APEX1 in the Endothelium Require the First 20 Amino Acids and Converge on Thioredoxin-1.Endoribonucleases--enzymes gaining spotlight in mRNA metabolism.Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein.Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.The many functions of APE1/Ref-1: not only a DNA repair enzymeAPE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsRedox control systems in the nucleus: mechanisms and functions.Posttranslational modification of mammalian AP endonuclease (APE1).Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells.Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondiiSpecific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell linesApurinic/apyrimidinic endonuclease 1 inhibits protein kinase C-mediated p66shc phosphorylation and vasoconstriction.Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor propertiesSubcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance.Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of cysteines 93 and 310Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis.Mitochondrial DNA, base excision repair and neurodegeneration.Differential expression of hepatic apurinic/apyrimidinic endonuclease 1, a DNA repair enzyme, in chronic hepatitis.Altered Secretory Activity of APE1/Ref-1 D148E Variants Identified in Human Patients With Bladder Cancer.Identification of cargo proteins specific for importin-β with importin-α applying a stable isotope labeling by amino acids in cell culture (SILAC)-based in vitro transport system.Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.Going ape as an approach to cancer therapeutics.Cytoplasmic localization and redox cysteine residue of APE1/Ref-1 are associated with its anti-inflammatory activity in cultured endothelial cells.Human apurinic/apyrimidinic endonuclease 1.Functions of disordered regions in mammalian early base excision repair proteins.Oxidized base damage and single-strand break repair in mammalian genomes: role of disordered regions and posttranslational modifications in early enzymes.Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway.Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress.Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).
P2860
Q24303442-B174E81B-9FBB-4ECA-931C-E96BDE978BFCQ24329154-6D13D7E0-2088-46E2-B82D-E5A466F7745AQ24647277-9E2FB0DF-86F1-4543-9BEE-4CF13DE9A21DQ24650179-C91E11E3-06BE-4F08-8582-EF02F984ECCBQ24816906-BE60BE7D-25BC-4736-B414-D9E97ACD2B8FQ26745611-001DCF07-E437-4AFD-95AF-D27AE2D8D0A3Q26777671-375BA863-4CB0-4BE6-AB9C-0482FE4A5A91Q26822957-E0E4672A-52CB-4380-B897-5F8EDE4B0923Q27026649-5F62C149-8D1E-4B81-BEA9-F8C36147940EQ28388989-4F86EFF8-0E58-4B35-B6C0-17F5E80DE144Q28583581-B49619C9-45AF-4700-AB60-08A722DEE7D6Q30275431-E736AF1C-EE4F-4BA5-A66A-91FFE0496800Q30383263-DC90DB18-5AAD-4D79-BC19-A6BB5EC6E9D1Q30434808-04DF34E5-6147-47C5-A095-285BA07263FEQ30497640-D3EC8101-1968-49EA-AAF2-6AB790405D90Q33609187-FDEF8F5D-7440-4B88-8F29-3ECF3EA3C85BQ33990581-23D82BEF-1CF4-4963-BC99-C70060A22C15Q34110120-909DF5E6-3CA8-4710-8659-944F8D7A0158Q34340923-57F1456F-E30C-49C7-BBAE-E219AD72BF61Q34547595-839D72AB-5443-4516-824A-7C2CDB24205DQ34883473-684B3A24-FB17-4DB8-8D64-B5DE8611DEBCQ34963206-A69D9A77-58CA-434F-9159-291C84638E0AQ35114763-F2BAEDFD-5AD4-4D94-A34A-4AC4A38980E3Q35599868-3A9C0E0B-A23E-484C-B67F-8179D88501A3Q35795731-FC997EA8-EDE7-4BF2-90E4-428ED105631CQ35829268-09F939C9-BB6C-44B3-9233-32882CE3BFFDQ35857124-B4EABB19-CF25-4DB1-81BA-3EBE49E063EDQ36223869-976692C2-AB1E-4FC6-ACBD-B206180C41F6Q36828516-4213530E-BA45-4BD5-B77E-93B13788CEA7Q36976131-D732A1FD-820F-4C70-9811-264D9C74276FQ37112673-CD9864F8-F75B-472A-B462-C99E8A861E2FQ37225608-43183C36-5EFE-4FF3-8F15-2C5AE0BE5CACQ37247774-BF7F37AC-380B-4924-9DDF-C5CC0F3DE72EQ37462479-E1788512-4344-4423-BE78-782762A7F996Q37512952-9564AD77-AA2B-432F-B405-1D6B87605F6DQ37780480-518D5448-D272-4708-870C-D32CA87B3B05Q38022936-C933F726-F0C0-416A-99A4-5B0FC707533FQ42007394-7373673A-B6BA-4C87-86F7-DF58F8DCCBBEQ42617617-3F2F9488-EF80-43E7-96E5-BD436B6F2465Q44740203-2E77F19C-7E32-46B7-9230-35437337C594
P2860
Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Analysis of nuclear transport ...... dinic endonuclease (APE1/Ref1)
@nl
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@ast
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@en
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@en-gb
type
label
Analysis of nuclear transport ...... dinic endonuclease (APE1/Ref1)
@nl
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@ast
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@en
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@en-gb
prefLabel
Analysis of nuclear transport ...... dinic endonuclease (APE1/Ref1)
@nl
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@ast
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@en
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@en-gb
P2093
P2860
P3181
P356
P1476
Analysis of nuclear transport ...... inic endonuclease (APE1/Ref1).
@en
P2093
Corey A Theriot
Elias B Jackson
Ranajoy Chattopadhyay
Sankar Mitra
Tadahide Izumi
P2860
P304
P3181
P356
10.1093/NAR/GKI641
P407
P577
2005-06-07T00:00:00Z