NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols
about
Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effectsNogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol traffickingRegulation of sterol transport between membranes and NPC2Functions of the alpha, beta, and gamma subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferaseArf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism.Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 DiseaseNiemann-Pick type C2 protein mediating chemical communication in the worker antThe promise and perils of HDAC inhibitors in neurodegenerationCharacterization of the Niemann-Pick C pathway in alveolar type II cells and lamellar bodies of the lungLoss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathwayNiemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 bindingProteins that bind and move lipids: MsbA and NPC1.Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis.Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrinPotential pitfalls and solutions for use of fluorescent fusion proteins to study the lysosomeThe cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteinsPharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein sheddingProteomic analysis of mouse models of Niemann-Pick C disease reveals alterations in the steady-state levels of lysosomal proteins within the brain.Unraveling the sterol-trafficking defect in Niemann-Pick C disease.Intracellular sterol dynamicsNiemann-Pick type C disease proteins: orphan transporters or membrane rheostats?Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells.Role of endosomes and lysosomes in human disease.Current controversies in Niemann-Pick C1 disease: steroids or gangliosides; neurons or neurons and glia.Treatment of Niemann--pick type C disease by histone deacetylase inhibitors.Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop.Common structural features of cholesterol binding sites in crystallized soluble proteins.Novel seminal fluid proteins in the seed beetle Callosobruchus maculatus identified by a proteomic and transcriptomic approach.Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1.Characterization of fluorescent sterol binding to purified human NPC1.Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin.Receptor-mediated and bulk-phase endocytosis cause macrophage and cholesterol accumulation in Niemann-Pick C disease.Are Niemann-Pick type C proteins key players in cnidarian-dinoflagellate endosymbioses?Functional characterization of a Niemann-Pick type C2 protein in the parasitoid wasp Microplitis mediator.NPC2 binds CHOLTransport Assays for Sterol-Binding Proteins: Stopped-Flow Fluorescence Methods for Investigating Intracellular Cholesterol Transport Mechanisms of NPC2 Protein.Large-scale computational drug repositioning to find treatments for rare diseases.Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts.
P2860
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P248
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P2860
NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
NPC2, the protein deficient in ...... that bind a variety of sterols
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NPC2, the protein deficient in ...... that bind a variety of sterols
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NPC2, the protein deficient in ...... that bind a variety of sterols
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NPC2, the protein deficient in ...... that bind a variety of sterols
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label
NPC2, the protein deficient in ...... that bind a variety of sterols
@ast
NPC2, the protein deficient in ...... that bind a variety of sterols
@en
NPC2, the protein deficient in ...... that bind a variety of sterols
@en-gb
NPC2, the protein deficient in ...... that bind a variety of sterols
@nl
prefLabel
NPC2, the protein deficient in ...... that bind a variety of sterols
@ast
NPC2, the protein deficient in ...... that bind a variety of sterols
@en
NPC2, the protein deficient in ...... that bind a variety of sterols
@en-gb
NPC2, the protein deficient in ...... that bind a variety of sterols
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P2093
P2860
P3181
P356
P1476
NPC2, the protein deficient in ...... that bind a variety of sterols
@en
P2093
G Stephen Tint
Heng-Ling Liou
Peter Lobel
Sayali S Dixit
P2860
P304
P3181
P356
10.1074/JBC.M608743200
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P50
P577
2006-12-01T00:00:00Z