Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.
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Niemann-Pick disease type CRole of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomesCCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein GlycosylationLoss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathwayProtein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 diseaseGene Atlasing of digestive and reproductive tissues in Schistosoma mansoniActivation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cellsSoluble proteins of chemical communication: an overview across arthropodsFluorescent Sterols and Cholesteryl Esters as Probes for Intracellular Cholesterol TransportEhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis.Proteins that bind and move lipids: MsbA and NPC1.A molecular analysis of desiccation tolerance mechanisms in the anhydrobiotic nematode Panagrolaimus superbus using expressed sequenced tags.Evolution of Chemosensory Gene Families in Arthropods: Insight from the First Inclusive Comparative Transcriptome Analysis across Spider AppendagesAdaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells.Abnormal gene expression in cerebellum of Npc1-/- mice during postnatal development.Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells.A novel role for Niemann-Pick disease type 2C protein in papillae formationCellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.Genetic connections between neurological disorders and cholesterol metabolismDeficiency of a Niemann-Pick, type C1-related protein in toxoplasma is associated with multiple lipidoses and increased pathogenicity.Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis.Cell cholesterol homeostasis: mediation by active cholesterolComparative analysis of the secretome from a model filarial nematode (Litomosoides sigmodontis) reveals maximal diversity in gravid female parasites.Insights into the mechanisms of sterol transport between organelles.A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking.Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation.Cholesterol in brain disease: sometimes determinant and frequently implicated.Synthesis, characterization, and evaluation of pluronic-based β-cyclodextrin polyrotaxanes for mobilization of accumulated cholesterol from Niemann-Pick type C fibroblasts.Characterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibodyAltered vitamin E status in Niemann-Pick type C disease.An "exacerbate-reverse" strategy in yeast identifies histone deacetylase inhibition as a correction for cholesterol and sphingolipid transport defects in human Niemann-Pick type C disease.Cholesterol metabolism and homeostasis in the brainDesign and synthesis of a crosslinker for studying intracellular steroid trafficking pathways.Niemann-Pick Type C-2 Disease: Identification by Analysis of Plasma Cholestane-3β,5α,6β-Triol and Further Insight into the Clinical Phenotype.Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C.Lysosome-associated membrane glycoprotein (LAMP)--preliminary study on a hidden antigen target for vaccination against schistosomiasisChanges on the Caco-2 secretome through differentiation analyzed by 2-D differential in-gel electrophoresis (DIGE).Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis.Antiestrogen-binding site ligands induce autophagy in myeloma cells that proceeds through alteration of cholesterol metabolismNiemann-Pick Type C2 Protein Mediates Hepatic Stellate Cells Activation by Regulating Free Cholesterol Accumulation
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P2860
Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.
@en
Niemann-Pick C2
@nl
type
label
Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.
@en
Niemann-Pick C2
@nl
prefLabel
Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.
@en
Niemann-Pick C2
@nl
P2860
P1476
Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.
@en
P2093
P2860
P304
P356
10.1016/J.BBALIP.2009.02.001
P407
P577
2009-02-13T00:00:00Z