Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase
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Cullin-RING ubiquitin ligases: global regulation and activation cyclesA coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligaseSmad3 prevents beta-catenin degradation and facilitates beta-catenin nuclear translocation in chondrocytesStructure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signalingStructural basis of selective ubiquitination of TRF1 by SCFFbx4Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligaseSCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) proteinPriming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substratePlk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complexStructural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationIdentification and characterization of a novel human PP1 phosphatase complexMutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's diseaseM-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCPThe ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survivalKeap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasomeSCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathwayIdentification, analysis, and prediction of protein ubiquitination sitesDiversity of degradation signals in the ubiquitin-proteasome systemA promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machineryWnt signaling: the good and the badSCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradationIdentification of a consensus site for TRAF6/p62 polyubiquitinationThe Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plateSequence and structural analysis of BTB domain proteinsJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsThe Ubiquitination of NF-κB Subunits in the Control of TranscriptionExpanding the ubiquitin code through post-translational modificationProtein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesShort linear motifs - ex nihilo evolution of protein regulationProtein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processesThe many faces and functions of β-cateninFunctional diversity and structural disorder in the human ubiquitination pathwayStructural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligaseCrystal Structure of a Full-Length β-CateninThe Prp19 WD40 Domain Contains a Conserved Protein Interaction Region Essential for Its FunctionA Dual E3 Mechanism for Rub1 Ligation to Cdc53
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P2860
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@ast
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@en
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@en-gb
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@nl
type
label
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@ast
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@en
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@en-gb
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@nl
prefLabel
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@ast
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@en
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@en-gb
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@nl
P2093
P921
P3181
P1433
P1476
Structure of a beta-TrCP1-Skp1 ...... F(beta-TrCP1) ubiquitin ligase
@en
P2093
Brenda A Schulman
Guozhou Xu
J Wade Harper
Nikola P Pavletich
Philip D Jeffrey
P304
P3181
P356
10.1016/S1097-2765(03)00234-X
P407
P577
2003-06-01T00:00:00Z