Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity
about
The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokineA novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytesEpstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietinLocal production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejectionAPC-derived cytokines and T cell polarization in autoimmune inflammationIncreased circulating interleukin-12 (IL-12) p40 in pulmonary sarcoidosisRegulation of IL-10 and IL-12 production and function in macrophages and dendritic cellsInterleukin 12: still a promising candidate for tumor immunotherapy?Interleukin 12 a key immunoregulatory cytokine in infection applicationsInvariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humansCloning and characterization of an adenoviral vector for highly efficient and doxycycline-suppressible expression of bioactive human single-chain interleukin 12 in colon cancer.Optimized expression and specific activity of IL-12 by directed molecular evolution.Human IL-12 p40 as a reporter gene for high-throughput screening of engineered mouse embryonic stem cellsTrypanosomiasis-induced Th17-like immune responses in carp.IL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responsesRecombinant herpes simplex virus type 1 (HSV-1) codelivering interleukin-12p35 as a molecular adjuvant enhances the protective immune response against ocular HSV-1 challengePulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltrationRole of interleukin-12 in primary influenza virus infectionA novel p40-independent function of IL-12p35 is required for progression and maintenance of herpes stromal keratitisRole of endogenous interleukin-18 in resolving wild-type and attenuated Salmonella typhimurium infections.Deficiency in the serum-derived hyaluronan-associated protein-hyaluronan complex enhances airway hyperresponsiveness in a murine model of asthmaRole of CD40 ligation in dendritic cell semimaturationInterleukin-12: an update on its immunological activities, signaling and regulation of gene expressionEffects of pegylated G-CSF on immune cell number and function in patients with gynecological malignanciesCerebrospinal fluid IL-12p40, CXCL13 and IL-8 as a combinatorial biomarker of active intrathecal inflammation.Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A.Regulation of lipopolysaccharide-induced interleukin-12 production by activation of repressor element GA-12 through hyperactivation of the ERK pathwayNovel immunocytokine IL12-SS1 (Fv) inhibits mesothelioma tumor growth in nude mice.A chimeric HIV-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF) domain induces enhanced antibody and T cell responses.IL12Rβ1: the cytokine receptor that we used to know.Sepsis and pathophysiology of anthrax in a nonhuman primate modelRecombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35Interleukin 12 and Th1 responses in inflammatory bowel diseaseIntracellular Salmonella dublin induces substantial secretion of the 40-kilodalton subunit of interleukin-12 (IL-12) but minimal secretion of IL-12 as a 70-kilodalton protein in murine macrophages.Lipopolysaccharide and monophosphoryl lipid A differentially regulate interleukin-12, gamma interferon, and interleukin-10 mRNA production in murine macrophages.An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivo.A multiscale systems perspective on cancer, immunotherapy, and Interleukin-12Accelerated wound healing phenotype in Interleukin 12/23 deficient mice.Synergistic interaction between Toll-like receptor agonists is required for induction of experimental autoimmune encephalomyelitis in Lewis ratsNovel IL27p28/IL12p40 cytokine suppressed experimental autoimmune uveitis by inhibiting autoreactive Th1/Th17 cells and promoting expansion of regulatory T cells
P2860
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P2860
Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@ast
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@en
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@en-gb
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@nl
type
label
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@ast
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@en
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@en-gb
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@nl
prefLabel
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@ast
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@en
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@en-gb
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@nl
P2093
P1476
Human IL-12 p40 homodimer bind ...... not mediate biologic activity
@en
P2093
Hollfelder K
P304
P407
P577
1995-01-01T00:00:00Z