Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes
about
SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptorsFrom noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locusSix new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humansThe glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytesGenetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities studyWNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathwayArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionalityAn ACAP1-containing clathrin coat complex for endocytic recyclingAcetylation of TUG protein promotes the accumulation of GLUT4 glucose transporters in an insulin-responsive intracellular compartmentSortilin, encoded by the cardiovascular risk gene SORT1, and its suggested functions in cardiovascular diseaseInsulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilinNRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell deathHypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay MiceGenome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architectureTUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recyclingInsulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesiclesGLUT4 is sorted to vesicles whose accumulation beneath and insertion into the plasma membrane are differentially regulated by insulin and selectively affected by insulin resistanceSelf-assembly of Glut4 storage vesicles during differentiation of 3T3-L1 adipocytesProteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signalingThe GLUT4 codeHigh basal cell surface levels of fish GLUT4 are related to reduced sensitivity of insulin-induced translocation toward GGA and AS160 inhibition in adipocytes.Stimulation of GLUT4 (glucose transporter isoform 4) storage vesicle formation by sphingolipid depletionInsulin-regulated Glut4 translocation: membrane protein trafficking with six distinctive steps.The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesiclesGLUT4 and UBC9 protein expression is reduced in muscle from type 2 diabetic patients with severe insulin resistance.The multi-level action of fatty acids on adiponectin production by fat cellsLeptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice.Sortilin: an unusual suspect in cholesterol metabolism: from GWAS identification to in vivo biochemical analyses, sortilin has been identified as a novel mediator of human lipoprotein metabolism.Antidiabetic Effect of Methanolic Extract from Berberis julianae Schneid. via Activation of AMP-Activated Protein Kinase in Type 2 Diabetic Mice.Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 myotubes.Glucagon like peptide-1-induced glucose metabolism in differentiated human muscle satellite cells is attenuated by hyperglycemiaTargeting steroid receptor coactivator 1 with antisense oligonucleotides increases insulin-stimulated skeletal muscle glucose uptake in chow-fed and high-fat-fed male ratsSac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytesSortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation.Physiology and pathology of endosome-to-Golgi retrograde sorting.Loss of AS160 Akt substrate causes Glut4 protein to accumulate in compartments that are primed for fusion in basal adipocytes.Dual-mode of insulin action controls GLUT4 vesicle exocytosis.The first luminal loop confers insulin responsiveness to glucose transporter 4.Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes
P2860
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P2860
Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@ast
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@en
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@en-gb
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@nl
type
label
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@ast
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@en
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@en-gb
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@nl
prefLabel
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@ast
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@en
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@en-gb
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@nl
P921
P3181
P1433
P1476
Sortilin is essential and suff ...... vesicles in 3T3-L1 adipocytes
@en
P2093
P304
P3181
P356
10.1016/J.DEVCEL.2005.04.004
P407
P577
2005-07-01T00:00:00Z