NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death
about
Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammationNGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling.Understanding proneurotrophin actions: Recent advances and challenges.P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury.Sortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation.Association between p75 neurotrophin receptor gene expression and cell apoptosis in tissues surrounding hematomas in rat models of intracerebral hemorrhage.Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action.Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.Role of Epithelial-Mesenchyme Transition in Chlamydia Pathogenesis.Detection of p75NTR Trimers: Implications for Receptor Stoichiometry and Activation.Sortilin and lipoprotein metabolism: making sense out of complexity.Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGFHippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer diseaseHuman LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model.Interleukin-1β enhances neuronal vulnerability to proNGF-mediated apoptosis by increasing surface expression of p75(NTR) and sortillin.Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR).The neurotrophins and their role in Alzheimer's disease.Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation.PROneurotrophins and CONSequences.Generation and characterization of mice bearing null alleles of nradd/Nrh2.Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.Sortilin limits EGFR signaling by promoting its internalization in lung cancer.
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NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
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im Juni 2009 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2009/06/03)
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vědecký článek publikovaný v roce 2009
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wetenschappelijk artikel (gepubliceerd op 2009/06/03)
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наукова стаття, опублікована в червні 2009
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مقالة علمية (نشرت في 3-6-2009)
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name
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
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NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@en
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
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type
label
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@ast
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@en
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@nl
prefLabel
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@ast
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@en
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@nl
P2860
P356
P1433
P1476
NRH2 is a trafficking switch t ...... eurotrophin-induced cell death
@en
P2093
Barbara L. Hempstead
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P304
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10.1038/EMBOJ.2009.118
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P577
2009-06-03T00:00:00Z