The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation
about
Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal traffickingAutolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interactionRin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradationBalanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/WntThe MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradationThe deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosomeBiogenesis and function of multivesicular bodiesAgonist-promoted Lys63-linked polyubiquitination of the human kappa-opioid receptor is involved in receptor down-regulationRegulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complexAMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradationSCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomesNeuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1The role of deubiquitinating enzymes in synaptic function and nervous system diseasesThe ESCRT machinery: from the plasma membrane to endosomes and back againProtein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesHybrid Structural Model of the Complete Human ESCRT-0 ComplexStructural Basis for ESCRT-III CHMP3 Recruitment of AMSHA Strategy for Modulation of Enzymes in the Ubiquitin SystemInsights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and ProductDual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies.Cell surface recycling in yeast: mechanisms and machineriesRegulation of endocytic sorting by ESCRT-DUB-mediated deubiquitinationThe diabetes susceptibility gene Clec16a regulates mitophagySystematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functionsEndocytosis and signalling: intertwining molecular networksCompetitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation.Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodiesMolecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex.IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.The HECT domain of the ubiquitin ligase Rsp5 contributes to substrate recognitionIntracellular trafficking and signaling in developmentDiacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8.G protein-coupled receptor sorting to endosomes and lysosomes.Molecular chaperones, cochaperones, and ubiquitination/deubiquitination system: involvement in the production of high quality spermatozoa.Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation
P2860
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P2860
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@ast
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@en
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@en-gb
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@nl
type
label
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@ast
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@en
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@en-gb
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@nl
prefLabel
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@ast
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@en
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@en-gb
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@nl
P50
P3181
P356
P1476
The ubiquitin isopeptidase UBP ...... l for receptor down-regulation
@en
P2093
Paula E Row
P304
P3181
P356
10.1074/JBC.M512615200
P407
P577
2006-05-05T00:00:00Z