IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.
about
PCSK9 inhibitors and cardiovascular disease: heralding a new therapeutic eraESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates Alzheimer disease pathology and restores neurogenesis.Clathrin-independent endocytosis: a cargo-centric viewCargo recognition in clathrin-mediated endocytosisMolecular and cellular function of the proprotein convertase subtilisin/kexin type 9 (PCSK9).The LXR-Idol axis differentially regulates plasma LDL levels in primates and micePathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments.PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice.A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes.Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake.The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.β-Estradiol results in a proprotein convertase subtilisin/kexin type 9-dependent increase in low-density lipoprotein receptor levels in human hepatic HuH7 cellsMolecular pathways: sterols and receptor signaling in cancer.Cellular cholesterol regulates ubiquitination and degradation of the cholesterol export proteins ABCA1 and ABCG1LDL cholesterol counteracts the antitumour effect of tyrosine kinase inhibitors against renal cell carcinoma.The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning.Reciprocal regulation of very low density lipoprotein receptors (VLDLRs) in neurons by brain-derived neurotrophic factor (BDNF) and Reelin: involvement of the E3 ligase Mylip/IdolFoiling IDOL to Help Control Cholesterol.Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.Clathrin-mediated endocytosis is a candidate entry sorting mechanism for Bombyx mori cypovirus.
P2860
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P2860
IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
IDOL stimulates clathrin-indep ...... -density lipoprotein receptor.
@ast
IDOL stimulates clathrin-indep ...... -density lipoprotein receptor.
@en
type
label
IDOL stimulates clathrin-indep ...... -density lipoprotein receptor.
@ast
IDOL stimulates clathrin-indep ...... -density lipoprotein receptor.
@en
prefLabel
IDOL stimulates clathrin-indep ...... -density lipoprotein receptor.
@ast
IDOL stimulates clathrin-indep ...... -density lipoprotein receptor.
@en
P2093
P2860
P356
P1476
IDOL stimulates clathrin-indep ...... -density lipoprotein receptor.
@en
P2093
Alice Y Ting
Chris N Goulbourne
Cynthia Hong
Elena Scotti
Francesco S Pavone
Jinkuk Choi
Loren G Fong
Martino Calamai
Paul F Pilch
P2860
P304
P356
10.1128/MCB.01716-12
P407
P577
2013-02-04T00:00:00Z