Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
about
VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surfaceCharacterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31Structural basis for Rab GTPase activation by VPS9 domain exchange factorsIdentification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recyclingRole of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growthRecycling Endosomes and Viral InfectionDynamic changes in the spatiotemporal localization of Rab21 in live RAW264 cells during macropinocytosisThe binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformationMultiple Roles of VARP in Endosomal Trafficking: Rabs, Retromer Components and R-SNARE VAMP7 Meet on VARPVarp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytesThe Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytesRab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells.BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriersRINL, guanine nucleotide exchange factor Rab5-subfamily, is involved in the EphA8-degradation pathway with odin.The ubiquitous dermokine delta activates Rab5 function in the early endocytic pathway.A role for Na+,K+-ATPase α1 in regulating Rab27a localisation on melanosomes.Deregulation of Rab and Rab effector genes in bladder cancer.Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.Differential regulation of Rab GTPase expression in monocyte-derived dendritic cells upon lipopolysaccharide activation: a correlation to maturation-dependent functional properties.Functional determinants of ras interference 1 mutants required for their inhbitory activity on endocytosis.Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling.Rab27a targeting to melanosomes requires nucleotide exchange but not effector bindingRabex-5 protein regulates dendritic localization of small GTPase Rab17 and neurite morphogenesis in hippocampal neuronsRab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes.Review series: Rab GTPases and membrane identity: causal or inconsequential?Lysosome-related organelles: unusual compartments become mainstream.Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.Rab27a and melanosomes: a model to investigate the membrane targeting of Rabs.Rab proteins of the endoplasmic reticulum: functions and interactors.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Retromer-mediated endosomal protein sorting: The role of unstructured domains.The Golgi apparatus: insights from filamentous fungi.Membrane traffic during axon development.Rab9A is required for delivery of cargo from recycling endosomes to melanosomes.Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes.Structural identification of the Vps18 β-propeller reveals a critical role in the HOPS complex stability and function.Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes.Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion.Measurement of Epidermal Growth Factor Receptor-Derived Signals Within Plasma Membrane Clathrin Structures.RAB21 GEFs exchange GTP for GDP on RAB21
P2860
Q24298162-DE43B2F2-FE71-4BCC-94B7-2D816F475E7CQ24303566-B1AC28F2-DEF4-42D9-ACE9-423E3690DDC9Q24303645-C9BCC655-4E80-41B4-9AEA-4C1EBD99903EQ24305023-E2B2D71C-B195-43B6-8ECA-07D33B70C788Q24315779-FA644519-41E6-41DB-915C-7A148D48953CQ26752566-933D09D0-6177-4F14-9C56-A42EEEAA3F37Q27343304-76D194A4-FE22-47F6-8137-A2D91A534A62Q27674764-C8ABBE29-B97E-42AE-8BC2-E3A8E40C1E71Q28071741-AFE9C366-4AD1-484A-B937-16E0845B60FBQ28505813-0F07D861-5374-48CE-A423-F2BB0D0FAC26Q28507877-5FE7D66A-6A55-4C99-83EF-F768DC9706F4Q30462793-81E264D5-551F-4FEA-B6F7-032C0CA798A0Q30793347-27466C95-B249-4705-9C39-209CCDB5E4DCQ31047089-C5D88E90-898A-4A09-A163-3F301AC9B87EQ33851719-D60B90AA-3E5C-4C9B-A6DD-A27B175FE7BAQ33933426-3CAC70E2-CDF0-4BE9-B7C2-67EAD45144A2Q34314461-848710FF-37F7-445F-8582-885DDF9DB895Q34606390-4084C480-8A17-4B5C-A6BC-88A4F322872FQ34988994-EA9BC953-D841-47B0-9A37-6DC78465F610Q35670752-86028DF6-6DA9-4319-BDBF-573AC72C3B98Q36091837-40D28C4C-F918-40B9-91B9-E615E0066D56Q36431914-3FF2BE9F-9416-47C6-BF51-6F6677D0FDD3Q36742238-43637E61-D91B-4DD7-9ECF-423930E63CE2Q36838770-FDF02F67-2E54-4B58-8C76-938061B28A30Q37034278-EA2F94EF-5388-4F25-B957-6F3B6A2E870CQ37060715-E4677775-05B0-4D0F-AEB6-70F6E4A4A2B7Q37616690-C28BCE93-96FF-4E3D-BA94-87C02A385946Q38061990-4D93F32C-2600-49CA-8976-79DA0FA79C11Q38061998-BDD05386-4FD9-4984-ACCE-29AED46DFC29Q38399347-1382896A-3253-48AC-B6B3-75A4F572CAE0Q38527246-2E686A51-F884-4FD4-9894-7127229BEDDFQ38756959-687F326E-77D0-49A8-8CC1-38B78E33607FQ38761954-06DC8192-A1DA-419C-86BB-D94F561D4B72Q41788193-22F930D4-2901-468D-83A5-23F453348CBDQ41789614-F9C253CC-707F-47B7-A245-719EC52BD65BQ42110307-9BC9254D-B360-4D23-814E-8C19B7EBD704Q42175722-443BD300-D0AF-4216-B14F-EE2995F5B030Q43192631-E4A9CCB8-D441-4AF4-8AF7-F1ED2CA988FCQ47974736-0FD07B54-C9FC-4EDA-BEE8-ADF3EFB01382Q50299992-3F311169-629C-4353-ACEA-BCD6CBA0E133
P2860
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@ast
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@en
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@en-gb
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@nl
type
label
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@ast
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@en
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@en-gb
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@nl
prefLabel
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@ast
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@en
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@en-gb
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@nl
P2093
P3181
P356
P1476
Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics
@en
P2093
Xin-Yuan Fu
Xinjun Zhang
Zhijie Chang
P304
P3181
P356
10.1242/JCS.02810
P407
P577
2006-03-15T00:00:00Z