Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
about
Rab1a and Rab5a preferentially bind to binary lipid compositions with higher stored curvature elastic energyRabGEFs are a major determinant for specific Rab membrane targetingThe interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.A role for Na+,K+-ATPase α1 in regulating Rab27a localisation on melanosomes.Inhibitory effect of 2-methyl-naphtho[1,2,3-de]quinolin-8-one on melanosome transport and skin pigmentation.The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting.Melanosomes on the move: a model to understand organelle dynamics.Rab27a and melanosomes: a model to investigate the membrane targeting of Rabs.Rab27 effectors, pleiotropic regulators in secretory pathways.The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targetinG tag.MADD exchanges GTP for GDP on RAB27
P2860
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P2860
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
@ast
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
@en
type
label
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
@ast
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
@en
prefLabel
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
@ast
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
@en
P2093
P2860
P1433
P1476
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
@en
P2093
Abul K Tarafder
Alistair N Hume
Ana C Figueiredo
Antonia E G Booth
Asumi Orihara
Christina Wasmeier
Jose S Ramalho
Miguel C Seabra
P2860
P304
P356
10.1111/J.1600-0854.2011.01216.X
P577
2011-06-15T00:00:00Z