The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity
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Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancerMutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndromeHow to form and close the brain: insight into the mechanism of cranial neural tube closure in mammalsRole of Telomerase in the Cardiovascular SystemLoss of Grainy head-like 1 is associated with disruption of the epidermal barrier and squamous cell carcinoma of the skinThe transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiationEpithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2Regulation of Transcription Factors by Reactive Oxygen Species and Nitric Oxide in Vascular Physiology and Pathology.Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.The functions of grainy head-like proteins in animals and fungi and the evolution of apical extracellular barriersGrhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression.Expression of transcription factor grainyhead-like 2 is diminished in cervical cancer.Mechanisms of tissue fusion during development.Lack of Association between Missense Variants in GRHL3 (rs2486668 and rs545809) and Susceptibility to Non-Syndromic Orofacial Clefts in a Han Chinese Population.Genome-scale study of transcription factor expression in the branching mouse lung.GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification.A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3.Grhl3 induces human epithelial tumor cell migration and invasion via downregulation of E-cadherinPost-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.The initial establishment and epithelial morphogenesis of the esophagus: a new model of tracheal-esophageal separation and transition of simple columnar into stratified squamous epithelium in the developing esophagus.Zebrafish models of orofacial clefts.Grainyhead-like Transcription Factors in Craniofacial Development.The role of barrier genes in epidermal malignancy.Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal CancerExpression and role of grainyhead-like 2 in gastric cancer.Neural tube closure: cellular, molecular and biomechanical mechanisms.Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2.Transcriptional mechanisms coordinating tight junction assembly during epithelial differentiation.Roles of Grainyhead-like transcription factors in cancer.Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3.Development and homeostasis of the skin epidermis.Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2.Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension.Grainyhead-like 2 (GRHL2) regulates epithelial plasticity in pancreatic cancer progression.Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers.Knockdown of GRHL3 inhibits activities and induces cell cycle arrest and apoptosis of human colorectal cancer cells.Grhl3 modulates epithelial structure formation of the circumvallate papilla during mouse development.Whole-Body Single-Cell Sequencing Reveals Transcriptional Domains in the Annelid Larval Body.
P2860
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P248
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P2860
The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
The unique and cooperative rol ...... pected target gene specificity
@ast
The unique and cooperative rol ...... pected target gene specificity
@en
The unique and cooperative rol ...... pected target gene specificity
@en-gb
The unique and cooperative rol ...... pected target gene specificity
@nl
type
label
The unique and cooperative rol ...... pected target gene specificity
@ast
The unique and cooperative rol ...... pected target gene specificity
@en
The unique and cooperative rol ...... pected target gene specificity
@en-gb
The unique and cooperative rol ...... pected target gene specificity
@nl
prefLabel
The unique and cooperative rol ...... pected target gene specificity
@ast
The unique and cooperative rol ...... pected target gene specificity
@en
The unique and cooperative rol ...... pected target gene specificity
@en-gb
The unique and cooperative rol ...... pected target gene specificity
@nl
P2093
P50
P921
P3181
P1476
The unique and cooperative rol ...... pected target gene specificity
@en
P2093
Alana Auden
Jacinta Caddy
Michael Cangkrama
Nikki R Hislop
Stephen B Ting
Stephen M Jane
Yeliz Boglev
P304
P3181
P356
10.1016/J.YDBIO.2010.11.011
P407
P577
2010-11-21T00:00:00Z