Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3.
about
Palatogenesis and cutaneous repair: A two-headed coinNew insights into craniofacial malformationsGene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotypeIdentification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell CarcinomaThe old and new face of craniofacial research: How animal models inform human craniofacial genetic and clinical dataInterferon regulatory factor 6 regulates keratinocyte migration.Periderm prevents pathological epithelial adhesions during embryogenesis.Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation.A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes.IRF6 Is Involved in the Regulation of Cell Proliferation and Transformation in MCF10A Cells Downstream of Notch SignalingExpression Analyses Revealed Thymic Stromal Co-Transporter/Slc46A2 Is in Stem Cell Populations and Is a Putative Tumor Suppressor.Lack of Association between Missense Variants in GRHL3 (rs2486668 and rs545809) and Susceptibility to Non-Syndromic Orofacial Clefts in a Han Chinese Population.Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development.Cellular and Molecular Mechanisms of PalatogenesisIrf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palateToward an orofacial gene regulatory network.A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3.Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm developmentAn etiologic regulatory mutation in IRF6 with loss- and gain-of-function effects.A toolbox to study epidermal cell types in zebrafish.Zebrafish models of orofacial clefts.IRF6 and SPRY4 Signaling Interact in Periderm Development.Grainyhead-like Transcription Factors in Craniofacial Development.Interferon Regulatory Factor 6 Promotes Keratinocyte Differentiation in Response to Porphyromonas gingivalis.IRF6 expression in basal epithelium partially rescues Irf6 knockout mice.The role of barrier genes in epidermal malignancy.Loss-of-Function GRHL3 Variants Detected in African Patients with Isolated Cleft Palate.Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure.TLR4 as a negative regulator of keratinocyte proliferation.Rapid functional analysis of computationally complex rare human IRF6 gene variants using a novel zebrafish model.Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension.Grhl3 modulates epithelial structure formation of the circumvallate papilla during mouse development.Grainyhead-like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety-like behaviors in aged mice.A Novel Interferon Regulatory Factor 6 Mutation in an Asian Family With Van der Woude Syndrome.Craniofacial genetics: Where have we been and where are we going?Shared molecular networks in orofacial and neural tube development
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P2860
Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Interferon regulatory factor 6 ...... pression of Grainyhead-like 3.
@en
type
label
Interferon regulatory factor 6 ...... pression of Grainyhead-like 3.
@en
prefLabel
Interferon regulatory factor 6 ...... pression of Grainyhead-like 3.
@en
P2093
P2860
P50
P356
P1476
Interferon regulatory factor 6 ...... xpression of Grainyhead-like 3
@en
P2093
Brian C Schutte
Cindy F Fukazawa
Daniel S Wagner
Douglas W Houston
Gabriel de la Garza
Gregory Bonde
Jason L Weirather
Martine Dunnwald
Stephen Butcher
P2860
P2888
P356
10.1038/JID.2012.269
P407
P577
2012-08-30T00:00:00Z