Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
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Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomesTWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcriptionBlue-Print Autophagy: Potential for Cancer TreatmentAutophagy in hepatocellular carcinomas: from pathophysiology to therapeutic responseOnto better TRAILs for cancer treatmentDED or alive: assembly and regulation of the death effector domain complexesCullin family proteins and tumorigenesis: genetic association and molecular mechanismsRegulation of CD95/Fas signaling at the DISCMicroRNA-mediated autophagic signaling networks and cancer chemoresistanceMicroRNAs in autophagy and their emerging roles in crosstalk with apoptosisRole of p62/SQSTM1 in liver physiology and pathogenesisTargeting autophagy for the treatment of liver diseasesModulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathwaysGetting TRAIL back on track for cancer therapyp62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk BodiesInsights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and ProductRegulation of inflammatory and antiviral signaling by A20.Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcomaThe ubiquitin system: a critical regulator of innate immunity and pathogen-host interactionsThe seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosisSelective autophagy mediated by autophagic adapter proteinsDoes antigen masking by ubiquitin chains protect from the development of autoimmune diseases?Macroautophagy is defective in mucolipin-1-deficient mouse neuronsMonobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells via the Wnt/β-Catenin Signaling PathwayCharacterizing ubiquitination sites by peptide-based immunoaffinity enrichment.Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin).RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKLONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells.The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8.Activation of JNK and IRE1 is critically involved in tanshinone I-induced p62 dependent autophagy in malignant pleural mesothelioma cells: implication of p62 UBA domain.Autophagy in the placenta.DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancerThe preclinical assessment of XL388, a mTOR kinase inhibitor, as a promising anti-renal cell carcinoma agentCurcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line.Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.p62 binding to protein kinase C ζ regulates tumor necrosis factor α-induced apoptotic pathway in endothelial cellsBortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex.Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways
P2860
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P2860
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@ast
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@en
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@en-gb
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@nl
type
label
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@ast
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@en
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@en-gb
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@nl
prefLabel
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@ast
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@en
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@en-gb
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@nl
P2093
P3181
P1433
P1476
Cullin3-based polyubiquitinati ...... extrinsic apoptosis signaling
@en
P2093
Avi Ashkenazi
David Lawrence
Jennie R Lill
Robert Pitti
Victoria C Pham
Zhaoyu Jin
P304
P3181
P356
10.1016/J.CELL.2009.03.015
P407
P577
2009-05-15T00:00:00Z