RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL - Wikidata - wikimedia - TriplyDB

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

http://www.wikidata.org/entity/Q30623992

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An outline of necrosome triggers Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis Death in the fast lane: what's next for necroptosis?DED or alive: assembly and regulation of the death effector domain complexes NET formation can occur independently of RIPK3 and MLKL signaling.Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis The intersection of cell death and inflammasome activation Key roles of necroptotic factors in promoting tumor growth The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer Fight or flight: regulation of emergency hematopoiesis by pyroptosis and necroptosis.Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis Deletion of FADD in macrophages and granulocytes results in RIP3- and MyD88-dependent systemic inflammation Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3 Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.New insights into the regulation of innate immunity by caspase-8.Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome.NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan.Border Security: The Role of RIPK3 in Epithelium Homeostasis.Evolutionary divergence of the necroptosis effector MLKL.Retinal pigment epithelial cell necroptosis in response to sodium iodate Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils.A dual role for Caspase8 and NF-κB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival Caspase-8: not so silently deadly.The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair The diverse role of RIP kinases in necroptosis and inflammation.Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.Macrophage cell death in microbial infections.A real-time fluorometric method for the simultaneous detection of cell death type and rate.RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.Participation of Necroptosis in the Host Response to Acute Bacterial Pneumonia.CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.Clinical Isolates of Pseudomonas aeruginosa from Chronically Infected Cystic Fibrosis Patients Fail To Activate the Inflammasome during Both Stable Infection and Pulmonary Exacerbation.Necroptosis-independent signaling by the RIP kinases in inflammation.

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

http://www.wikidata.org/entity/Q30623992

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

@ast

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

@en

type

label

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

@ast

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

@en

prefLabel

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

@ast

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

@en

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Nature Communications

P1476

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

@en

P2093

Alison Mildenhall

http://www.w3.org/2001/XMLSchema#string

Cathrine Hall

http://www.w3.org/2001/XMLSchema#string

Christopher A Benetatos

http://www.w3.org/2001/XMLSchema#string

Ian P Wicks

http://www.w3.org/2001/XMLSchema#string

James E Vince

http://www.w3.org/2001/XMLSchema#string

Nufail Khan

http://www.w3.org/2001/XMLSchema#string

Stephen M Condon

http://www.w3.org/2001/XMLSchema#string

Sukhdeep Kaur Spall

http://www.w3.org/2001/XMLSchema#string

Warren S Alexander

http://www.w3.org/2001/XMLSchema#string

Yasuhiro Mitsuuchi

http://www.w3.org/2001/XMLSchema#string

P2860

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

TRPM2 links oxidative stress to NLRP3 inflammasome activation

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6282

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scholarly article

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10.1038/NCOMMS7282

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P478

6

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W. Wei-Lynn Wong

Akshay A D'Cruz

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2015-02-18T00:00:00Z

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272515242

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1004672525

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25693118

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4346630

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