Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
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Crystallographic insight into collagen recognition by discoidin domain receptor 2Conformational coupling across the plasma membrane in activation of the EGF receptorEGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatmentEGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastomaCell signaling by receptor tyrosine kinasesErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylationStructure-function relationships of ErbB RTKs in the plasma membrane of living cellsDesign principles underpinning the regulatory diversity of protein kinasesEnhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancerOrchestration of ErbB3 signaling through heterointeractions and homointeractions.Inhibition of Receptor Dimerization as a Novel Negative Feedback Mechanism of EGFR SignalingCoarse-grained molecular simulation of epidermal growth factor receptor protein tyrosine kinase multi-site self-phosphorylationConformational Changes in the Epidermal Growth Factor Receptor: Role of the Transmembrane Domain Investigated by Coarse-Grained MetaDynamics Free Energy CalculationsSingle Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated PitsStructural analysis of the catalytically inactive kinase domain of the human EGF receptor 3Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF ReceptorAssessing the range of kinase autoinhibition mechanisms in the insulin receptor familyErlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domainAck1: Activation and Regulation by AllosteryStructure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human PathologiesCrystal structures of the phosphorylated BRI1 kinase domain and implications for brassinosteroid signal initiationAn ATP-Competitive Inhibitor Modulates the Allosteric Function of the HER3 PseudokinaseA genetically encoded 19F NMR probe for tyrosine phosphorylationEpidermal growth factor: a new therapeutic target in glomerular disease.The molecular circuitry of brassinosteroid signalingIdentifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinasesP130Cas attenuates epidermal growth factor (EGF) receptor internalization by modulating EGF-triggered dynamin phosphorylationA potential peptide therapeutic derived from the juxtamembrane domain of the epidermal growth factor receptorModeling Cellular Noise Underlying Heterogeneous Cell Responses in the Epidermal Growth Factor Signaling PathwayA graph theoretic approach to utilizing protein structure to identify non-random somatic mutations.Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution MicroscopyStructure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.The growing story of (ARABIDOPSIS) CRINKLY 4.Understanding single-pass transmembrane receptor signaling from a structural viewpoint-what are we missing?Targeting kinase signaling pathways with constrained peptide scaffolds.Effects of clinically relevant MPL mutations in the transmembrane domain revealed at the atomic level through computational modeling.Computational modeling of allosteric communication reveals organizing principles of mutation-induced signaling in ABL and EGFR kinases.The energy landscape analysis of cancer mutations in protein kinasesLineage-specific co-evolution of the Egf receptor/ligand signaling system.Discoidin domain receptor functions in physiological and pathological conditions.
P2860
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P2860
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mechanism for activation of th ...... n by the juxtamembrane segment
@ast
Mechanism for activation of th ...... n by the juxtamembrane segment
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Mechanism for activation of th ...... n by the juxtamembrane segment
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Mechanism for activation of th ...... n by the juxtamembrane segment
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type
label
Mechanism for activation of th ...... n by the juxtamembrane segment
@ast
Mechanism for activation of th ...... n by the juxtamembrane segment
@en
Mechanism for activation of th ...... n by the juxtamembrane segment
@en-gb
Mechanism for activation of th ...... n by the juxtamembrane segment
@nl
altLabel
Mechanism for Activation of th ...... n by the Juxtamembrane Segment
@en
prefLabel
Mechanism for activation of th ...... n by the juxtamembrane segment
@ast
Mechanism for activation of th ...... n by the juxtamembrane segment
@en
Mechanism for activation of th ...... n by the juxtamembrane segment
@en-gb
Mechanism for activation of th ...... n by the juxtamembrane segment
@nl
P2093
P2860
P3181
P1433
P1476
Mechanism for activation of th ...... n by the juxtamembrane segment
@en
P2093
David E Wemmer
Kate Engel
Meindert H Lamers
Natalia Jura
Nicholas F Endres
Xuewu Zhang
P2860
P304
P3181
P356
10.1016/J.CELL.2009.04.025
P407
P577
2009-06-26T00:00:00Z