PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase
about
Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylasesHistone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial developmentPHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progressionHistone demethylases in chromatin biology and beyondStructural and functional coordination of DNA and histone methylationEpigenetic regulation by histone demethylases in hypoxiaStructural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase FamilyLinking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylasesThe Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic developmentInhibition of 2-oxoglutarate dependent oxygenasesMETTL23, a transcriptional partner of GABPA, is essential for human cognition.NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.Phf8 loss confers resistance to depression-like and anxiety-like behaviors in miceDevelopment of homogeneous luminescence assays for histone demethylase catalysis and binding.Developmental epigenetics of the murine secondary palateThe Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin SignalingCoordinated chromatin control: structural and functional linkage of DNA and histone methylation.A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylasesDynamics of histone lysine methylation: structures of methyl writers and erasersSmall-molecular modulators of cancer-associated epigenetic mechanisms.Dysregulation of RNA polymerase I transcription during disease.Palate morphogenesis: current understanding and future directions.A study of cleft lip/palate in a community in the South East of GhanaMassSQUIRM: An assay for quantitative measurement of lysine demethylase activityCoordinated methyl-lysine erasure: structural and functional linkage of a Jumonji demethylase domain and a reader domain.Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders.The Histone Demethylase PHF8 Is Essential for Endothelial Cell Migration.Plant homeodomain fingers form a helping hand for transcription.Structure and function of histone H3 lysine 9 methyltransferases and demethylases.Chromatin as an oxygen sensor and active player in the hypoxia response.Chemical biology of lysine demethylases.Breathing-in epigenetic change with vitamin C.Jumonji family histone demethylases in neural development.Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: a TRAnsition to targeted therapies.Writing, erasing and reading histone lysine methylations.The histone demethylase PHF8 is essential for cytoskeleton dynamics.(Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators.PHF8 targets histone methylation and RNA polymerase II to activate transcription.
P2860
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P2860
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase
description
2010 nî lūn-bûn
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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2010 թվականի հունվարին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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name
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@ast
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@en
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@en-gb
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@nl
type
label
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@ast
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@en
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@en-gb
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@nl
prefLabel
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@ast
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@en
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@en-gb
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@nl
P2860
P50
P3181
P356
P1476
PHF8, a gene associated with c ...... on-dimethyl lysine demethylase
@en
P2093
Robert J Klose
P2860
P304
P3181
P356
10.1093/HMG/DDP480
P407
P50
P577
2009-10-19T00:00:00Z