Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells
about
Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectinMolecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene familyChromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene familyHuman corneal GlcNac 6-O-sulfotransferase and mouse intestinal GlcNac 6-O-sulfotransferase both produce keratan sulfateMacular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase geneBeta 1,4-galactosyltransferase (beta 4GalT)-IV is specific for GlcNAc 6-O-sulfate. Beta 4GalT-IV acts on keratan sulfate-related glycans and a precursor glycan of 6-sulfosialyl-Lewis X.Cancer-associated alternative usage of multiple promoters of human GalCer sulfotransferase gene.Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5).Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.Modifications of glycans: biological significance and therapeutic opportunitiesA major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules.Preferential induction of peripheral lymph node addressin on high endothelial venule-like vessels in the active phase of ulcerative colitis.Prominent expression of sialyl Lewis X-capped core 2-branched O-glycans on high endothelial venule-like vessels in gastric MALT lymphomaRegulation of selectin binding activity by cyclization of sialic acid moiety of carbohydrate ligands on human leukocytes.Reconstitution of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of alpha1-->3 fucosyltransferase VII and newly cloned GlcNAcbeta:6-sulfotransferase cDNA.Endothelial ligands for L-selectin: from lymphocyte recirculation to allograft rejection.The systems biology of glycosylation.Expression of long-form N-acetylglucosamine-6-O-sulfotransferase 1 in human high endothelial venules.Sulfation of a high endothelial venule-expressed ligand for L-selectin. Effects on tethering and rolling of lymphocytesSystems-level studies of glycosyltransferase gene expression and enzyme activity that are associated with the selectin binding function of human leukocytes.GlcNAc6ST-1-mediated decoration of MAdCAM-1 protein with L-selectin ligand carbohydrates directs disease activity of ulcerative colitisRole of sulfated O-glycans expressed by high endothelial venule-like vessels in pathogenesis of chronic inflammatory gastrointestinal diseases.KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain.Minimal sulfated carbohydrates for recognition by L-selectin and the MECA-79 antibody.N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing.Apical membrane expression of distinct sulfated glycans represents a novel marker of cholangiolocellular carcinoma.Human B-lymphocytes express alpha2-6-sialylated 6-sulfo-N-acetyllactosamine serving as a preferred ligand for CD22/Siglec-2.Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-alpha.Significance of NF-kappaB/GATA axis in tumor necrosis factor-alpha-induced expression of 6-sulfated cell recognition glycans in human T-lymphocytes.Structural analysis of sulfated N-linked oligosaccharides in erythropoietin.Region-specific and epileptogenic-dependent expression of six subtypes of alpha2,3-sialyltransferase in the adult mouse brain.Role of MAdCAM-1-Expressing High Endothelial Venule-Like Vessels in Colitis Induced in Mice Lacking Sulfotransferases Catalyzing L-Selectin Ligand Biosynthesis.Induction of high endothelial venule-like vessels expressing GlcNAc6ST-1-mediated L-selectin ligand carbohydrate and mucosal addressin cell adhesion molecule 1 (MAdCAM-1) in a mouse model of "Candidatus Helicobacter heilmannii"-induced gastritis and
P2860
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P2860
Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@ast
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@en
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@en-gb
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@nl
type
label
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@ast
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@en
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@en-gb
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@nl
prefLabel
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@ast
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@en
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@en-gb
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@nl
P2093
P1476
Human N-acetylglucosamine-6-O- ...... various organs and tumor cells
@en
P2093
A Nakagawara
C Mitsuoka
H Muramatsu
I Yokoyama
K Kadomatsu
K Uchimura
K Yamamura
P356
10.1093/OXFORDJOURNALS.JBCHEM.A022164
P407
P577
1998-09-01T00:00:00Z