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Modifications of glycans: biological significance and therapeutic opportunities

Modifications of glycans: biological significance and therapeutic opportunities

http://www.wikidata.org/entity/Q34111293

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Polysaccharide nanosystems for future progress in cardiovascular pathologies Glycotherapy: new advances inspire a reemergence of glycans in medicine Complement factor H, vitronectin, and opticin are tyrosine-sulfated proteins of the retinal pigment epithelium Mammalian protein glycosylation--structure versus function.Glycan Reader is Improved to Recognize Most Sugar Types and Chemical Modifications in the Protein Data Bank.Fibulin 2, a tyrosine O-sulfated protein, is up-regulated following retinal detachment.Sugar-modified foldamers as conformationally defined and biologically distinct glycopeptide mimics Glycosyltransferases: carb loading strategy is spot on.Metabolic fate of neutral human milk oligosaccharides in exclusively breast-fed infants.Perspectives on Anti-Glycan Antibodies Gleaned from Development of a Community Resource Database The third dimension of reading the sugar code by lectins: design of glycoclusters with cyclic scaffolds as tools with the aim to define correlations between spatial presentation and activity.Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry.Shaping up for structural glycomics: a predictive protocol for oligosaccharide conformational analysis applied to N-linked glycans.Novel spatiotemporal glycome changes in the murine placenta during placentation based on BS-I lectin binding patterns.Simple sugars to complex disease--mucin-type O-glycans in cancer.Transcriptional Activity of Heparan Sulfate Biosynthetic Machinery is Specifically Impaired in Benign Prostate Hyperplasia and Prostate Cancer.Anharmonic simulations of the vibrational spectrum of sulfated compounds: application to the glycosaminoglycan fragment glucosamine 6-sulfate.Carbene-mediated functionalization of the anomeric C-H bond of carbohydrates: scope and limitations.Over forty years of bladder cancer glycobiology: Where do glycans stand facing precision oncology?A novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodies.Activation energies of fragmentations of disaccharides by tandem mass spectrometry.Differentiation of isomeric β-(1-4) hexose disaccharides by positive electrospray tandem mass spectrometry

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Modifications of glycans: biological significance and therapeutic opportunities

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2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2012年の論文

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Modifications of glycans: biological significance and therapeutic opportunities

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Modifications of glycans: biological significance and therapeutic opportunities

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Modifications of glycans: biological significance and therapeutic opportunities

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ACS Chemical Biology

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Modifications of glycans: biological significance and therapeutic opportunities

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Christopher T Campbell

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Jeffrey C Gildersleeve

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Saddam M Muthana

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P2860

Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88

Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects

Structural basis for recognition of phosphodiester-containing lysosomal enzymes by the cation-independent mannose 6-phosphate receptor

The role and metabolism of sulfatide in the nervous system

Ferulic acid: an antioxidant found naturally in plant cell walls and feruloyl esterases involved in its release and their applications

Mycolic acids: structure, biosynthesis and physiological functions

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31-43

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10.1021/CB2004466

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