Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis - Wikidata - wikimedia - TriplyDB

Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis

Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis

http://www.wikidata.org/entity/Q24309609

about

The functional interactome landscape of the human histone deacetylase family Protein kinase D in vascular biology and angiogenesis Protein kinase D regulates RhoA activity via rhotekin phosphorylation.Identification of protein kinase D2 as a pivotal regulator of endothelial cell proliferation, migration, and angiogenesis Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin Protein Kinase D1 Signaling in Angiogenic Gene Expression and VEGF-Mediated Angiogenesis Protein Kinase D Enzymes as Regulators of EMT and Cancer Cell Invasion Epigenetic regulation of endothelial-cell-mediated vascular repair Post-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and disease Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.AMP-activated protein kinase mediates myogenin expression and myogenesis via histone deacetylase 5 Targeting vascular endothelial growth factor receptor 2 and protein kinase D1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro MEF2 is regulated by CaMKIIδ2 and a HDAC4-HDAC5 heterodimer in vascular smooth muscle cells VEGFA-VEGFR2 Signaling Pathway Novel mechanism of gene transfection by low-energy shock wave.Design, Synthesis, and Biological Evaluation of PKD Inhibitors.Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility.CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS Parathyroid hormone regulates histone deacetylase (HDAC) 4 through protein kinase A-mediated phosphorylation and dephosphorylation in osteoblastic cells PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy.Protein kinase D as a potential new target for cancer therapy.Role of protein kinase D signaling in pancreatic cancer Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77 Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity.AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5.Lysophosphatidic acid suppresses endothelial cell CD36 expression and promotes angiogenesis via a PKD-1-dependent signaling pathway.Receptor-independent protein kinase C alpha (PKCalpha) signaling by calpain-generated free catalytic domains induces HDAC5 nuclear export and regulates cardiac transcription.Histone deacetylase inhibitors enhance endothelial cell sprouting angiogenesis in vitro Protein kinase D signaling: multiple biological functions in health and disease.Roles and post-translational regulation of cardiac class IIa histone deacetylase isoforms.A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells.Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting RAGE Signaling in Diabetic Atherosclerosis.HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration Chronic valproate treatment enhances postischemic angiogenesis and promotes functional recovery in a rat model of ischemic stroke Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow.

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Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis

http://www.wikidata.org/entity/Q24309609

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008年の論文

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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type

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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prefLabel

Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

@en

Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Protein kinase D-dependent pho ...... ne expression and angiogenesis

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Angelika Hausser

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Chang Hoon Ha

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Chelsea Wong

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Eric N Olson

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Klaus Pfizenmaier

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Timothy A McKinsey

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Weiye Wang

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Zheng-Gen Jin

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P2860

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5

The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis

The biology of VEGF and its receptors

Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2

Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

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14590-9

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1681879

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10.1074/JBC.M800264200

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21

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283

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18332134

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positive regulation of angiogenesis

Protein kinase D1

phosphorylation

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2386927

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