Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1
about
Sphingolipids: a potential molecular approach to treat allergic inflammationCalcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cellsCIB1 is a regulator of pathological cardiac hypertrophyThe compartmentalization and translocation of the sphingosine kinases: mechanisms and functions in cell signaling and sphingolipid metabolismSphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progressSolution Structures of Ca 2+ -CIB1 and Mg 2+ -CIB1 and Their Interactions with the Platelet Integrin αIIb Cytoplasmic DomainSphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor MicroenvironmentStructure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.Sphingosine kinase 1 isoform-specific interactions in breast cancerCIB1 contributes to oncogenic signalling by Ras via modulating the subcellular localisation of sphingosine kinase 1CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation.Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphateSphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cellsMembranes in balance: mechanisms of sphingolipid homeostasis.An update on sphingosine-1-phosphate and other sphingolipid mediators.Capitalizing on diversity: an integrative approach towards the multiplicity of cellular mechanisms underlying myogenic responsiveness.Coupling between endocytosis and sphingosine kinase 1 recruitment.CIB1 synergizes with EphrinA2 to regulate Kaposi's sarcoma-associated herpesvirus macropinocytic entry in human microvascular dermal endothelial cells.Sphingosine-1-phosphate signaling and its role in disease.Sphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond.Sphingosine kinase 1 as an anticancer therapeutic target.Sphingosine kinase 1 knockdown reduces insulin synthesis and secretion in a rat insulinoma cell lineCIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer.Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter releaseIntracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner.Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells.Binding of CIB1 to the αIIb tail of αIIbβ3 is required for FAK recruitment and activation in plateletsLocalized sphingolipid signaling at presynaptic terminals is regulated by calcium influx and promotes recruitment of priming factors.Inhibition of VEGFR2 Activation and Its Downstream Signaling to ERK1/2 and Calcium by Thrombospondin-1 (TSP1): In silico InvestigationImmune regulation by sphingosine 1-phosphate and its receptors.Sphingosine kinase 1 in viral infections.Sphingosine kinase and sphingosine-1-phosphate: regulators in autoimmune and inflammatory disease.CIB1: a small protein with big ambitions.Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies.CIB1 and CIB2 are HIV-1 helper factors involved in viral entry.Enhanced expression of transferrin receptor 1 contributes to oncogenic signalling by sphingosine kinase 1.Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways.Assessing the ligand selectivity of sphingosine kinases using molecular dynamics and MM-PBSA binding free energy calculations.
P2860
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P2860
Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Translocation of sphingosine k ...... and integrin-binding protein 1
@ast
Translocation of sphingosine k ...... and integrin-binding protein 1
@en
Translocation of sphingosine k ...... and integrin-binding protein 1
@en-gb
Translocation of sphingosine k ...... and integrin-binding protein 1
@nl
type
label
Translocation of sphingosine k ...... and integrin-binding protein 1
@ast
Translocation of sphingosine k ...... and integrin-binding protein 1
@en
Translocation of sphingosine k ...... and integrin-binding protein 1
@en-gb
Translocation of sphingosine k ...... and integrin-binding protein 1
@nl
prefLabel
Translocation of sphingosine k ...... and integrin-binding protein 1
@ast
Translocation of sphingosine k ...... and integrin-binding protein 1
@en
Translocation of sphingosine k ...... and integrin-binding protein 1
@en-gb
Translocation of sphingosine k ...... and integrin-binding protein 1
@nl
P2093
P2860
P921
P3181
P356
P1476
Translocation of sphingosine k ...... and integrin-binding protein 1
@en
P2093
Julia R Zebol
Kate E Jarman
Paul A B Moretti
P2860
P304
P3181
P356
10.1074/JBC.M109.068395
P407
P577
2009-10-23T00:00:00Z