The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line
about
The sodium leak channel, NALCN, in health and diseaseSodium leak channels in neuronal excitability and rhythmic behaviorsConserved role of unc-79 in ethanol responses in lightweight mutant miceA Conserved Bicycle Model for Circadian Clock Control of Membrane ExcitabilityDe novo mutations in NALCN cause a syndrome characterized by congenital contractures of the limbs and face, hypotonia, and developmental delay.A uniquely adaptable pore is consistent with NALCN being an ion sensorThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsA co-operative regulation of neuronal excitability by UNC-7 innexin and NCA/NALCN leak channelLoss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- miceThe interplay of seven subthreshold conductances controls the resting membrane potential and the oscillatory behavior of thalamocortical neurons.A sodium leak current regulates pacemaker activity of adult central pattern generator neurons in Lymnaea stagnalis.NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channelsNovel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications.Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulationUNC79 and UNC80, putative auxiliary subunits of the NARROW ABDOMEN ion channel, are indispensable for robust circadian locomotor rhythms in DrosophilaMathematical modeling of heterogeneous electrophysiological responses in human β-cellsPancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational AnalysisBursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.Sodium leak channel, non-selective contributes to the leak current in human myometrial smooth muscle cells from pregnant womenPhylogeny unites animal sodium leak channels with fungal calcium channels in an ancient, voltage-insensitive clade.Rare DNA copy number variants in cardiovascular malformations with extracardiac abnormalitiesIon channels and regulation of insulin secretion in human β-cells: a computational systems analysisThe cellular building blocks of breathingThe leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.Involvement of Na(+)-leak channel in substance P-induced depolarization of pacemaking activity in interstitial cells of Cajal.Extrasynaptic muscarinic acetylcholine receptors on neuronal cell bodies regulate presynaptic function in Caenorhabditis elegansMutations in NALCN cause an autosomal-recessive syndrome with severe hypotonia, speech impairment, and cognitive delay.Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals.The prelude on novel receptor and ligand targets involved in the treatment of diabetes mellitus.NALCN: a regulator of pacemaker activity.Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels.The role of M(3)-muscarinic receptor signaling in insulin secretion.G protein-coupled receptor signaling via Src kinase induces endogenous human transient receptor potential vanilloid type 6 (TRPV6) channel activation.Induction of a novel cation current in cardiac ventricular myocytes by flufenamic acid and related drugs.NALCN: a regulated leak channelDopamine negatively modulates the NCA ion channels in C. elegans.The truth in complexes: perspectives on ion channel signaling nexuses in the nervous system.Food deprivation and nicotine correct akinesia and freezing in Na(+) -leak current channel (NALCN)-deficient strains of Caenorhabditis elegans.Autocrine activation of P2Y1 receptors couples Ca (2+) influx to Ca (2+) release in human pancreatic beta cells.
P2860
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P2860
The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line
description
2009 nî lūn-bûn
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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
@zh-hk
2009年論文
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2009年論文
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2009年论文
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The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@ast
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@en
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@en-gb
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@nl
type
label
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@ast
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@en
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@en-gb
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@nl
prefLabel
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@ast
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@en
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@en-gb
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The NALCN ion channel is activ ...... in a pancreatic beta-cell line
@en
P2093
Alexandre Mezghrani
Annie Varrault
Gyslaine Bertrand
Leigh Anne Swayne
Richard J Miller
Stephane Dalle
P2860
P304
P3181
P356
10.1038/EMBOR.2009.125
P407
P577
2009-07-03T00:00:00Z