Sodium leak channels in neuronal excitability and rhythmic behaviors
about
mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic stateThe sodium leak channel, NALCN, in health and diseaseUsing the canary genome to decipher the evolution of hormone-sensitive gene regulation in seasonal singing birdsNalcn Is a "Leak" Sodium Channel That Regulates Excitability of Brainstem Chemosensory Neurons and Breathing.De novo mutations in NALCN cause a syndrome characterized by congenital contractures of the limbs and face, hypotonia, and developmental delay.A uniquely adaptable pore is consistent with NALCN being an ion sensorInhibition of the TRPC5 ion channel protects the kidney filterThe voltage-gated sodium channel TPC1 confers endolysosomal excitability.The Narrow Abdomen Ion Channel Complex Is Highly Stable and Persists from Development into Adult Stages to Promote Behavioral Rhythmicity.The interplay of seven subthreshold conductances controls the resting membrane potential and the oscillatory behavior of thalamocortical neurons.Transcriptome analysis of the human corneal endothelium.Lysosomal physiology.UNC79 and UNC80, putative auxiliary subunits of the NARROW ABDOMEN ion channel, are indispensable for robust circadian locomotor rhythms in DrosophilaGd3+ and calcium sensitive, sodium leak currents are features of weak membrane-glass seals in patch clamp recordingsSubstance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels.Non-linear leak currents affect mammalian neuron physiology.Risk factors and outcomes associated with new-onset atrial fibrillation during acute respiratory distress syndrome.Phylogeny unites animal sodium leak channels with fungal calcium channels in an ancient, voltage-insensitive clade.Biallelic Mutations in UNC80 Cause Persistent Hypotonia, Encephalopathy, Growth Retardation, and Severe Intellectual DisabilityThe leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.Kch1 family proteins mediate essential responses to endoplasmic reticulum stresses in the yeasts Saccharomyces cerevisiae and Candida albicans.Ih Equalizes Membrane Input Resistance in a Heterogeneous Population of Fusiform Neurons in the Dorsal Cochlear Nucleus.Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals.NALCN: a regulator of pacemaker activity.Defective lipid metabolism in neurodegeneration with brain iron accumulation (NBIA) syndromes: not only a matter of iron.Forward-genetics analysis of sleep in randomly mutagenized mice.De novo missense mutations in NALCN cause developmental and intellectual impairment with hypotonia.UNC80 mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channel NALCN.Calcium regulation of spontaneous and asynchronous neurotransmitter release.How Cells Can Control Their Size by Pumping Ions.Novel NALCN variant: altered respiratory and circadian rhythm, anesthetic sensitivity.Dopamine negatively modulates the NCA ion channels in C. elegans.A non-inactivating high-voltage-activated two-pore Na⁺ channel that supports ultra-long action potentials and membrane bistability.Identification of novel therapeutic target genes and pathway in pancreatic cancer by integrative analysis.Responsiveness of voltage-gated calcium channels in SH-SY5Y human neuroblastoma cells on micropillar substrates.Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling.Respiratory Network Stability and Modulatory Response to Substance P Require Nalcn.Akinesia and freezing caused by Na+ leak-current channel (NALCN) deficiency corrected by pharmacological inhibition of K+ channels and gap junctions.Starting physiology: bioelectrogenesis.Lack of current observed in HEK293 cells expressing NALCN channels.
P2860
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P2860
Sodium leak channels in neuronal excitability and rhythmic behaviors
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Sodium leak channels in neuronal excitability and rhythmic behaviors
@ast
Sodium leak channels in neuronal excitability and rhythmic behaviors
@en
Sodium leak channels in neuronal excitability and rhythmic behaviors
@nl
type
label
Sodium leak channels in neuronal excitability and rhythmic behaviors
@ast
Sodium leak channels in neuronal excitability and rhythmic behaviors
@en
Sodium leak channels in neuronal excitability and rhythmic behaviors
@nl
prefLabel
Sodium leak channels in neuronal excitability and rhythmic behaviors
@ast
Sodium leak channels in neuronal excitability and rhythmic behaviors
@en
Sodium leak channels in neuronal excitability and rhythmic behaviors
@nl
P2860
P3181
P1433
P1476
Sodium leak channels in neuronal excitability and rhythmic behaviors
@en
P2093
Dejian Ren
P2860
P304
P3181
P356
10.1016/J.NEURON.2011.12.007
P407
P577
2011-12-22T00:00:00Z