Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
about
Pro-urokinase-type plasminogen activator is a substrate for hepsinMatriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteinsHepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymesPla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterolMouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissuesHepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancersCorin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart.Localization of the mosaic transmembrane serine protease corin to heart myocytes.Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation.The role of the cell-cell interactions in cancer progression.Regulators of gene expression as biomarkers for prostate cancerHepatitis B virus X protein binding to hepsin promotes C3 production by inducing IL-6 secretion from hepatocytes.Membrane-anchored serine proteases in health and disease.Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model.Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease.High Hepsin expression predicts poor prognosis in Gastric Cancer.TMPRSS4 induces invasion and proliferation of prostate cancer cells through induction of Slug and cyclin D1.Gene expression analysis of prostate cancers.Cellular consequences of thrombin-receptor activation.Complete nucleotide sequence, origin of isoform and functional characterization of the mouse hepsin gene.Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice.Identification and cloning of the membrane-associated serine protease, hepsin, from mouse preimplantation embryos.HPN heterodimer cleaves pro-HGF to form HGF dimerHPN heterodimer cleaves pro-MST1 to form MST1 dimer
P2860
Q24299743-97C10743-0711-4808-A951-FBEBB9DAC7E4Q24302437-3ECF7C49-81A7-4005-B869-973676D56DB3Q27863809-F9A1DA30-C5E4-4D07-BDB5-CBEE0ED84528Q28142811-6CFF1C11-C4CD-4BFF-9B95-66E2ED98D11CQ28591047-9A996064-8D7D-47DF-A09D-EA7E687E9CE2Q28593308-6B1F881C-41E0-4E1E-9DB0-7900918BD4B3Q31161402-2155E7BA-8B75-43B6-B0AD-74F9DD2C4D40Q33862279-951B17C2-7689-44F3-9CEE-3BD472AD16BCQ33925569-148CA988-5812-4CC6-9016-B46A896FB534Q34315470-DC6BCC7D-F4A2-4DBC-9EEB-D10275DC8A9BQ35531372-C30566CC-A314-4AC6-8110-E3CFAFD3EF06Q36439912-AF03C026-085F-4D50-9330-34A31273EB8DQ36946624-88EB06A2-2F54-4FE7-B401-0722EAF13928Q36969010-02F32769-E761-42E4-BC16-3B19116AAF86Q37122556-DD177A1B-6398-47E9-8542-85468571C762Q37377341-EF78A93F-520E-464C-9D1D-6B636E7376A1Q37411864-89A5DBE7-BF0F-466F-8ADB-6A67F45733FEQ39626323-310CA4E3-B167-4F24-8800-E0A5E364F37CQ40664417-84585FF4-6A01-4FB0-888A-68EAC72FF42AQ40952373-24979CB0-AA93-4F1E-8858-85005FB205BBQ42475017-EA6EE1A4-8E55-439B-B802-2D4831B29BCAQ47315721-A5C729CB-EDC8-4ACC-A759-15B02912B3BBQ48040546-0940A1FC-3708-4CD9-9E62-E6C86374AFD1Q50298084-E7E9DDD1-83DC-4358-B860-11031E5A31A0Q50298147-8C2AC5E9-637A-41CC-A142-5402F48A65DD
P2860
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@ast
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@en
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@en-gb
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@nl
type
label
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@ast
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@en
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@en-gb
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@nl
prefLabel
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@ast
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@en
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@en-gb
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@nl
P2093
P2860
P921
P3181
P356
P1476
Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth
@en
P2093
A Torres-Rosado
K S O'Shea
P2860
P304
P3181
P356
10.1073/PNAS.90.15.7181
P407
P50
P577
1993-08-01T00:00:00Z