Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease.
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Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzymePro-urokinase-type plasminogen activator is a substrate for hepsinMatriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivityMouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexesIdentification and characterization of human and mouse ovastacin: a novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fishHepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymesThyroxine treatments do not correct inner ear defects in tmprss1 mutant mice.Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycansMice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss.Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterolMouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissuesHageman factor, platelets and polyphosphates: early history and recent connectionHepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancersCorin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart.Zebrafish as a model system for the study of hemostasis and thrombosis.Phenotypic analysis of mice lacking the Tmprss2-encoded proteaseCorin in natriuretic peptide processing and hypertensionc-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptasePolyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.Identification of hepsin and protein disulfide isomerase A3 as targets of gelatinolytic action in rat ovarian granulosa cells during the periovulatory periodCorin in clinical laboratory diagnosticsModeling Disorders of Blood Coagulation in the Zebrafish.The role of platelet and endothelial GARP in thrombosis and hemostasis.Discovery and fine mapping of serum protein loci through transethnic meta-analysisThe serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model.The role of type II transmembrane serine protease-mediated signaling in cancer.HLA-A2-restricted cytotoxic T lymphocyte epitopes from human hepsin as novel targets for prostate cancer immunotherapy.Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.Complete nucleotide sequence, origin of isoform and functional characterization of the mouse hepsin gene.Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice.Matriptase inhibition by hepatocyte growth factor activator inhibitor-1 is essential for placental development
P2860
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P2860
Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Generation and characterizatio ...... transmembrane serine protease.
@en
Generation and characterizatio ...... transmembrane serine protease.
@nl
type
label
Generation and characterizatio ...... transmembrane serine protease.
@en
Generation and characterizatio ...... transmembrane serine protease.
@nl
prefLabel
Generation and characterizatio ...... transmembrane serine protease.
@en
Generation and characterizatio ...... transmembrane serine protease.
@nl
P2093
P2860
P356
P1476
Generation and characterizatio ...... transmembrane serine protease.
@en
P2093
P2860
P304
P356
10.1172/JCI1617
P407
P577
1998-01-01T00:00:00Z