The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
about
PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland developmentThe intracellular domain of ErbB4 induces differentiation of mammary epithelial cellsInteractions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathwaysTyrosine phosphorylation controls PCNA function through protein stabilityPhosphorylation of ErbB4 on tyrosine 1056 is critical for ErbB4 coupling to inhibition of colony formation by human mammary cell linesNeuregulin3 alters cell fate in the epidermis and mammary glandNon-canonical signaling mode of the epidermal growth factor receptor familyReceptor tyrosine kinases in the nucleusKinase-independent mechanisms of resistance of leukemia stem cells to tyrosine kinase inhibitorsMiz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylationProteolytic Processing of ErbB4 in Breast CancerNuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cellsLoss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formationThe E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradationThe ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cellsIdentification of nucleolin as new ErbB receptors- interacting proteinCell death or survival promoted by alternative isoforms of ErbB4Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infectionCharacterization of the archaeal thermophile Sulfolobus turreted icosahedral virus validates an evolutionary link among double-stranded DNA viruses from all domains of lifeNuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain.HMGN2 inducibly binds a novel transactivation domain in nuclear PRLr to coordinate Stat5a-mediated transcription.Expression and function of heregulin-alpha and its receptors in the mouse mammary gland.The interaction of the ErbB4 intracellular domain p80 with α-enolase in the nuclei is associated with the inhibition of the neuregulin1-dependent cell proliferation.The localization of HER4 intracellular domain and expression of its alternately-spliced isoforms have prognostic significance in ER+ HER2- breast cancer.Nuclear trafficking of the epidermal growth factor receptor family membrane proteins.The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product s80HER4.The role of HER2 in cancer therapy and targeted drug deliveryHypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary glandSignaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivoDeletion of ErbB4 accelerates polycystic kidney disease progression in cpk mice.Molecular targeting to treat gastric cancer.Estrogen receptor coregulators and pioneer factors: the orchestrators of mammary gland cell fate and development.Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells.The epidermal growth factor receptor family: biology driving targeted therapeutics.Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation.HER4 in breast cancer: comparison of antibodies against intra- and extra-cellular domains of HER4
P2860
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P2860
The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@ast
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@en
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@en-gb
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@nl
type
label
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@ast
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@en
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@en-gb
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@nl
prefLabel
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@ast
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@en
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@en-gb
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@nl
P2093
P2860
P921
P3181
P356
P1476
The ERBB4/HER4 receptor tyrosi ...... as a STAT5A nuclear chaperone
@en
P2093
Barbara S Beckman
Christopher C Williams
Frank E Jones
Gregory A Vidal
June G Allison
Luis Marrero
Matthew E Burow
P2860
P304
P3181
P356
10.1083/JCB.200403155
P407
P577
2004-11-08T00:00:00Z