Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family
about
Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinaseA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisUnique carboxyl-terminal sequences of wild type and alternatively spliced variant forms of transforming growth factor-alpha precursors mediate specific interactions with ErbB4 and ErbB2Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytesHeregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3Mechanism of activation and inhibition of the HER4/ErbB4 kinaseThe ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperoneAssociation of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cellsBinding of Neu differentiation factor with the extracellular domain of Her2 and Her3Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferationDistribution of mRNA for human epiregulin, a differentially expressed member of the epidermal growth factor familyAnalysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptorsCytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signallingFailure of spinal cord oligodendrocyte development in mice lacking neuregulinSolution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4Identification of c-erbB-3 binding sites for phosphatidylinositol 3'-kinase and SHC using an EGF receptor/c-erbB-3 chimeraRetroviral oncogenes: a historical primerCharacterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampusSomatic mutations of the epidermal growth factor receptor and non-small-cell lung cancerMedullary carcinoma is associated with expression of intercellular adhesion molecule-1. Implication to its morphology and its clinical behaviorErbB receptors: from oncogenes to targeted cancer therapiesFunctional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.Heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor in normal and neoplastic hematopoiesisHeparin binding-epidermal growth factor-like growth factor for the regeneration of chronic tympanic membrane perforations in mice.A differential requirement for the COOH-terminal region of the epidermal growth factor (EGF) receptor in amphiregulin and EGF mitogenic signalingSensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90Identification of a heregulin binding site in HER3 extracellular domainThe N-terminal region of NTAK/neuregulin-2 isoforms has an inhibitory activity on angiogenesisTransformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour typesHeregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinaseDefects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapsesStimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channelsARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathwayErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactationTumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4The cellular response to neuregulins is governed by complex interactions of the erbB receptor family
P2860
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P2860
Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Ligand-specific activation of ...... growth factor receptor family
@ast
Ligand-specific activation of ...... growth factor receptor family
@en
Ligand-specific activation of ...... growth factor receptor family
@en-gb
Ligand-specific activation of ...... growth factor receptor family
@nl
type
label
Ligand-specific activation of ...... growth factor receptor family
@ast
Ligand-specific activation of ...... growth factor receptor family
@en
Ligand-specific activation of ...... growth factor receptor family
@en-gb
Ligand-specific activation of ...... growth factor receptor family
@nl
prefLabel
Ligand-specific activation of ...... growth factor receptor family
@ast
Ligand-specific activation of ...... growth factor receptor family
@en
Ligand-specific activation of ...... growth factor receptor family
@en-gb
Ligand-specific activation of ...... growth factor receptor family
@nl
P2093
P2860
P356
P1476
Ligand-specific activation of ...... growth factor receptor family
@en
P2093
G D Plowman
G S Whitney
G W Carlton
J M Culouscou
M G Neubauer
P2860
P304
P356
10.1073/PNAS.90.5.1746
P407
P577
1993-03-01T00:00:00Z